Results 11 to 20 of about 19,763,054 (100)

3-Iodothyroacetic acid (TA 1 ), a by-product of thyroid hormone metabolism, reduces the hypnotic effect of ethanol without interacting at GABA-A receptors

open access: yesNeurochemistry International, 2018
3-iodothyroacetic acid (TA1) is among the by-products of thyroid hormone metabolism suspected to mediate the non-genomic effects of the hormone (T3). We aim to investigate whether TA1 systemically administered to mice stimulated mice wakefulness, an effect already described for T3 and for another T3 metabolite (i.e.
Laurino A   +6 more
openaire   +4 more sources

The 3-iodothyroacetic acid does not cause change in proteins affected by T1AM.

open access: yes, 2021
The 3-iodothyroacetic acid (TA1) derives from the metabolism of 3-iodothyronamine and it is highly produced in cell culture medium supplemented with fetal bovine serum. Previous results indicated that, in models of brain cell lines, exogenous T1AM can increase the phosphorylation of proteins involved in signaling cascade, but this could be a ...
Bandini L.   +4 more
openaire   +2 more sources

Behavioral and metabolic effects of 3-iodothyroacetic acid: role of histamine

open access: yes, 2014
Objectives: 3-iodothyroacetic acid (TA1) is the major catabolite of 3-iodothyronamine in most tissues. The aim of the present work is to determine whether TA1 is physiologically present in rodent brain and whether administration of exogenous TA1 can produce significant functional effects.
Manni ME   +6 more
openaire   +2 more sources

Anticonvulsant and neuroprotective actions of 3-iodothyroacetic acid (TA1), a by- product of thyroid hormone metabolism in epilepsy models

open access: yes, 2017
Background and Purpose: We recently reported 3-iodothyroacetic acid (TA1), a metabolite of thyroid hormone, stimulated learning and gave hyperal-gesia activating the histaminergic system. We now aim to investigate whether TA1 could induce other typical histamine-dependent effects including increase of attention of vigilance and of wakefulness ...
Laurino, A.   +7 more
core   +3 more sources

Regulation of Arabidopsis 14-3-3 gene expression by GABA. [PDF]

open access: yes, 2006
The function in plants of the non-protein amino acid, gamma-aminobutyric acid (GABA) is poorly understood. In this study, we show that GABA down-regulates the expression of a large sub-set of 14-3-3 gene family members in Arabidopsis thaliana seedlings ...
Lancien, Muriel, Roberts, Michael R
core   +5 more sources

Bile Acid Induced Diarrhoea Pathophysiological and Clinical Aspects [PDF]

open access: yes, 2008
A common cause for referral to gastroenterologists is chronic watery diarrhoea. Approximately 40% of these patients have idiopathic bile acid malabsorption (BAM) – a condition with unknown aetiology.
Bajor, Antal
core   +1 more source

Cytenamide-butyric acid (1/1) [PDF]

open access: yes, 2008
Cytenamide forms a 1:1 solvate with butyric acid [systematic name: 5H-dibenzo[a,d]cycloheptatriene-5-carboxamide-butanoic acid (1/1)], C16H13NO·C4H8O2.
Florence, A.J.   +4 more
core   +4 more sources

3-Carboxyanilinium 3-carboxy-4-hydroxybenzenesulfonate: the 1:1 proton-transfer compound of 5-sulfosalicylic acid with 3-aminobenzoic acid [PDF]

open access: yes, 2005
The crystal structure of the anhydrous 1:1 proton-transfer compound of 5-sulfosalicylic acid (3-carboxy-4-hydroxybenzenesulfonic acid) with 3-aminobenzoic acid, C7H8NO2+·C7H5O6S-, shows heteromeric cyclic R22(8) carboxylic acid dimers formed through ...
Smith, Graham
core   +1 more source

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