Pharmacological effects of 3-iodothyronamine (T1AM) in mice include facilitation of memory acquisition and retention and reduction of pain threshold. [PDF]
Manni ME +11 more
europepmc +1 more source
BRAFV600E mutation contributes papillary thyroid carcinoma and Hashimoto thyroiditis with resistance to thyroid hormone: A case report and literature review. [PDF]
Xing W, Liu X, He Q, Zhang Z, Jiang Z.
europepmc +1 more source
Thyroid Hormone Biomonitoring: A Review on Their Metabolism and Machine-Learning Based Analysis on Effects of Endocrine Disrupting Chemicals. [PDF]
Chen S +9 more
europepmc +1 more source
Identification and quantification of 3-iodothyronamine metabolites in mouse serum using liquid chromatography-tandem mass spectrometry. [PDF]
Hackenmueller SA, Scanlan TS.
europepmc +1 more source
Mapping variants in thyroid hormone transporter MCT8 to disease severity by genomic, phenotypic, functional, structural and deep learning integration. [PDF]
Groeneweg S +121 more
europepmc +1 more source
Transport, Metabolism, and Function of Thyroid Hormones in the Developing Mammalian Brain. [PDF]
Stepien BK, Huttner WB.
europepmc +1 more source
Redox Properties of 3-Iodothyronamine (T1AM) and 3-Iodothyroacetic Acid (TA1) [PDF]
3-iodothyronamine (T1AM) and 3-iodothyroacetic acid (TA1) are thyroid-hormone-related compounds endowed with pharmacological activity through mechanisms that remain elusive. Some evidence suggests that they may have redox features. We assessed the chemical activity of T1AM and TA1 at pro-oxidant conditions.
Maura Lodovici +2 more
exaly +10 more sources
Histamine mediates behavioural and metabolic effects of 3-iodothyroacetic acid, an endogenous end product of thyroid hormone metabolism [PDF]
Background and Purpose3‐Iodothyroacetic acid (TA1) is an end product of thyroid hormone metabolism. So far, it is not known ifTA1is present in mouse brain and if it has any pharmacological effects.Experimental ApproachTA1levels in mouse brain were measured byHPLCcoupled to mass spectrometry. After i.c.v.
Gustavo Provensi +2 more
exaly +6 more sources
The 3-iodothyronamine (T1AM) and 3-iodothryoacetic acid (TA1), are endogenous occurring compounds structurally related with thyroid hormones (THs, the pro-hormone T4 and the active hormone T3) initially proposed as possible mediators of the rapid effects of T3.
Annunziatina Laurino +2 more
exaly +5 more sources

