Results 71 to 80 of about 19,763,054 (100)

Pharmacological effects of 3-iodothyronamine (T1AM) in mice include facilitation of memory acquisition and retention and reduction of pain threshold. [PDF]

open access: yesBr J Pharmacol, 2013
Manni ME   +11 more
europepmc   +1 more source

Mapping variants in thyroid hormone transporter MCT8 to disease severity by genomic, phenotypic, functional, structural and deep learning integration. [PDF]

open access: yesNat Commun
Groeneweg S   +121 more
europepmc   +1 more source

Redox Properties of 3-Iodothyronamine (T1AM) and 3-Iodothyroacetic Acid (TA1) [PDF]

open access: yesInternational Journal of Molecular Sciences, 2022
3-iodothyronamine (T1AM) and 3-iodothyroacetic acid (TA1) are thyroid-hormone-related compounds endowed with pharmacological activity through mechanisms that remain elusive. Some evidence suggests that they may have redox features. We assessed the chemical activity of T1AM and TA1 at pro-oxidant conditions.
Maura Lodovici   +2 more
exaly   +10 more sources

Histamine mediates behavioural and metabolic effects of 3-iodothyroacetic acid, an endogenous end product of thyroid hormone metabolism [PDF]

open access: yesBritish Journal of Pharmacology, 2014
Background and Purpose3‐Iodothyroacetic acid (TA1) is an end product of thyroid hormone metabolism. So far, it is not known ifTA1is present in mouse brain and if it has any pharmacological effects.Experimental ApproachTA1levels in mouse brain were measured byHPLCcoupled to mass spectrometry. After i.c.v.
Gustavo Provensi   +2 more
exaly   +6 more sources

The 3-iodothyronamine (T1AM) and the 3-iodothyroacetic acid (TA1) indicate a novel connection with the histamine system for neuroprotection

open access: yesEuropean Journal of Pharmacology, 2021
The 3-iodothyronamine (T1AM) and 3-iodothryoacetic acid (TA1), are endogenous occurring compounds structurally related with thyroid hormones (THs, the pro-hormone T4 and the active hormone T3) initially proposed as possible mediators of the rapid effects of T3.
Annunziatina Laurino   +2 more
exaly   +5 more sources

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