Results 11 to 20 of about 19,351,043 (289)

Synthesis and Characterization of Gefitinib and Paclitaxel Mono and Dual Drug-Loaded Blood Cockle Shells (Anadara granosa)-Derived Aragonite CaCO₃ Nanoparticles

Nanomaterials, 2021
Calcium carbonate has slowly paved its way into the field of nanomaterial research due to its inherent properties: biocompatibility, pH-sensitivity, and slow biodegradability.
S. Chemmalar, Abdul Razak Intan-Shameha, Che Azurahanim Che Abdullah, Nor Asma Ab Razak, Loqman Mohamad Yusof, Mokrish Ajat, N. S. K. Gowthaman, Md Zuki Abu Bakar   +7 more
doaj   +1 more source

The Protective Effect of Egb 761 Against 3-Nitropropionic Acid-Induced Hearing Loss: The Role of Sirtuin 1 [PDF]

Clinical and Experimental Otorhinolaryngology, 2018
Objectives Local administration of 3-nitropropionic acid (3-NP) to the inner ear induces sensorineural hearing loss. Several studies have shown the otoprotective effects of ginkgo biloba extract EGb 761.
Mun Young Chang, Jihye Rhee, Shin Hye Kim, Young Ho Kim   +3 more
doaj   +1 more source

Nanoplastic Exposure at Predicted Environmental Concentrations Induces Activation of Germline Ephrin Signal Associated with Toxicity Formation in the Caenorhabditis elegans Offspring

Toxics, 2022
In nematode Caenorhabditis elegans, exposure to polystyrene nanoparticles (PS-NPs) at predicted environmental concentrations can cause induction of transgenerational toxicity.
Yue Zhao, Xin Hua, Qian Bian, Dayong Wang   +3 more
doaj   +1 more source

Pre-Anodized Graphite Pencil Electrode Coated with a Poly(Thionine) Film for Simultaneous Sensing of 3-Nitrophenol and 4-Nitrophenol in Environmental Water Samples

Sensors, 2022
A very simple, as well as sensitive and selective, sensing protocol was developed on a pre-anodized graphite pencil electrode surface coated using poly(thionine) (APGE/PTH). The poly(thionine) coated graphite pencil was then used for simultaneous sensing
Vijaya Gopalan Sree, Jung Inn Sohn, Hyunsik Im   +2 more
doaj   +1 more source

Inhibition of Estrogenic Response of Yeast Screen Assay by Exposure to Non-Lethal Levels of Metallic Nanoparticles

Applied Sciences, 2020
In order to investigate the effects of metallic nanoparticles (NPs) on the performance of in vitro bioassay, zinc oxide NP (ZnO NP), aluminum oxide NP (Al2O3 NP), bare silver NP (Ag NP), and Ag NP capped with citrate (Agcit NP) were evaluated with yeast (
Byoung-cheun Lee, Cuong N. Duong, Jungkon Kim, Suejin Kim, Ig-chun Eom, Pilje Kim   +5 more
doaj   +1 more source

Genotoxic effects of 1-nitropyrene in macrophages are mediated through a p53-dependent pathway involving cytochrome c release, caspase activation, and PARP-1 cleavage

Ecotoxicology and Environmental Safety, 2021
Genotoxic stress from environmental pollutants plays a critical role in cytotoxicity. The most abundant nitro-polycyclic aromatic hydrocarbon in environmental pollutants, 1-nitropyrene (1-NP), is generated during fossil fuel, diesel, and biomass ...
Sheng-Wen Wu, Chun-Hung Su, Yung-Chuan Ho, Rosa Huang-Liu, Ching-Chi Tseng, Yun-Wei Chiang, Kun-Lin Yeh, Shiuan-Shinn Lee, Wen-Ying Chen, Chun-Jung Chen, Yi-Ching Li, Chien-Ying Lee, Yu-Hsiang Kuan   +12 more
doaj   +1 more source

Non-enzymatic primer extension with strand displacement

eLife, 2019
Non-enzymatic RNA self-replication is integral to the emergence of the ‘RNA World’. Despite considerable progress in non-enzymatic template copying, demonstrating a full replication cycle remains challenging due to the difficulty of separating the ...
Lijun Zhou, Seohyun Chris Kim, Katherine H Ho, Derek K O'Flaherty, Constantin Giurgiu, Tom H Wright, Jack W Szostak   +6 more
doaj   +1 more source

Raw data of the effects of Chlorogenic acid in 3-Nitropropionic acid induced toxicity and genotoxicity

Data in Brief, 2017
The raw data showed in this article comes from the published research article entitled “Protective effects of Chlorogenic acid in 3-Nitropropionic acid induced toxicity and genotoxicity” Food Chem Toxicol. 2017 May 3. pii: S0278-6915(17)30226-0.
Alarcón-Herrera Norberto, Flores-Maya Saúl, Bellido Belén, M. García-Bores Ana, Mendoza Ernesto, Ávila-Acevedo Guillermo, Hernández-Echeagaray Elizabeth   +6 more
doaj   +1 more source

Effect of safranal or candesartan on 3-nitropropionicacid-induced biochemical, behavioral and histological alterations in a rat model of Huntington's disease.

PLoS ONE, 2023
3-nitropropionic acid (3-NP) is a potent mitochondrial inhibitor mycotoxin. Systemic administration of 3-NP can induce Huntington's disease (HD)-like symptoms in experimental animals. Safranal (Safr) that is found in saffron essential oil has antioxidant,
Nagwa Ibrahim Shehata, Dina Mohamed Abd El-Salam, Roqaya Mahmoud Hussein, Sherine Maher Rizk   +3 more
doaj   +1 more source

Mitochondrial-dependent apoptosis in Huntington's disease human cybrids [PDF]

, 2010
We investigated the involvement of mitochondrial-dependent apoptosis in Huntington's disease (HD) vs. control (CTR) cybrids, obtained from the fusion of human platelets with mitochondrial DNA-depleted NT2 cells, and further exposed to 3-nitropropionic ...
Almeida, S, Cardoso, SM, Ferreira, IL, Grazina, M, Januário, C, Nascimento, MV, Oliveira, CR, Pratas, J, Rego, AC, Ribeiro, MH, Santos, MJ   +10 more
core   +1 more source