Results 21 to 30 of about 13,770,514 (290)
462.A.1.10(2).pdf created from original election material in the South African Elections Collection held in the Manuscripts Section of the Stellenbosch Library and Information Service.Campaign poster by the National Party (NP) encouraging South Africans ...
core
Evidence of dysregulation of the CREB/CRE transcriptional pathway in animal models of Huntington's disease (HD) suggests that strategies designed to augment CRE-mediated transcription may be of therapeutic value. Here, we investigated the consequences of
Yun-Sik Choi +7 more
doaj +1 more source
Background/Aims: Previous studies have shown that oxidative damage is a main contributor to disc nucleus pulposus (NP) cell apoptosis. Aquaporin-3 (AQP-3) facilitates reactive oxygen species (ROS) scavenging and thus alleviates oxidative injury in other ...
Yichun Xu +7 more
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HMGB1 Promotes Mitochondrial Dysfunction-Triggered Striatal Neurodegeneration via Autophagy and Apoptosis Activation. [PDF]
Impairments in mitochondrial energy metabolism are thought to be involved in many neurodegenerative diseases. The mitochondrial inhibitor 3-nitropropionic acid (3-NP) induces striatal pathology mimicking neurodegeneration in vivo. Previous studies showed
Lin Qi +19 more
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Brain-derived neurotrophic factor (BDNF) deficiency and mitochondrial dysfunction have been implicated in the pathogenesis of Huntington's disease (HD).
Chia-Lin Wu +4 more
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Metabolic impairment of neurons has been implicated in several neurological disorders, but it is not at present known whether such metabolic impairment has deleterious effects on microglia, the phagocytic cells of the central nervous system (CNS). In the
Jae K Ryu +5 more
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This study was performed to determine the effects of chitosan-coated nano-propolis (NP), which is synthesized via a green sonochemical method, and propolis on the side effects of cisplatin (CP), which is a widely used drug in the treatment of cancer. For
Pinar Tatli Seven +6 more
doaj +1 more source
Determining PR8-NP-intNL mRNA splicing rates and virus stability in cell culture.
(A) Top: Diagram of “NP-int/NP” (yellow) and “NP-int only” (green) dye-based qPCR primer locations on PR8 NP-intNL mRNAs. Bottom, left: Absolute standard curve detecting “NP-int/NP” and “NP-int only” sequences from a plasmid containing an PR8 NP intron ...
Kaitlyn N. Burke (10885460) +6 more
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In the present in vivo study, we provide a comparison of toxicological consequences induced by four different types of spherical nanoparticles (NPs)—silver nanoparticles (AgNPs, 40 ± 6 nm), nickel (NiNPs, 43 ± 6 nm), cobalt oxide ...
Zakia Kanwal +6 more
doaj +1 more source
Nutritional programming improves dietary plant protein utilization in zebrafish Danio rerio.
Nutritional Programming (NP) has been shown to counteract the negative effects of dietary plant protein (PP) by introducing PP at an early age towards enhancement of PP utilization during later life stages.
Karolina Kwasek +5 more
doaj +1 more source

