Efeitos do ácido 3-nitropropiônico (3-NP) na inervação extrínseca do coração de camundongos - modelo experimental para a doença de Huntington [PDF]
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Temporomandibular Disorders and Orofacial Outcomes in Subjects with Neck Pain and/or Cervicogenic Headache: A Systematic Review with Meta-Analysis. [PDF]
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Influence of the Intervertebral Disc Microenvironment on Matrix Synthesis and Metabolism in Goat Nucleus Pulposus Cells. [PDF]
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Recent Progress in Advanced Electrode Materials for the Detection of 4-Nitrophenol and Its Derivatives for Environmental Monitoring. [PDF]
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Reimagining primary care delivery: Evaluation of nurse practitioner-owned primary care practices. [PDF]
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Neuroprotective potential of Cilostazol in 3-NP provoked Huntington's disease-associated symptoms
Research Journal of Pharmacy and Technology, 2021Huntington's disease (HD), a neurodegenerative condition specified by mitochondrial deficits, psychiatric and cognitive impairment developed due to neuronal damage in the brain.
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Current Protocols in Neuroscience, 2014AbstractThe mitochondrial toxin 3‐nitropropionic acid (3‐NP) is an irreversible inhibitor of respiratory chain complex II. Chronic systemic administration of 3‐NP to mice, rats, and non‐human primates leads to preferential degeneration of the striatum, and produces motor and cognitive symptoms that are highly reminiscent of Huntington's disease (HD ...
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