Results 251 to 260 of about 13,770,514 (290)

Protein Disulfide Isomerase Disassembles TDP‐43/G3BP1 Condensates and Antagonizes TDP‐43 Pathological Aggregates

Advanced Science, EarlyView.
Cytoplasmic aggregation of TDP‐43 is a common pathological feature in amyotrophic lateral sclerosis, frontotemporal lobar degeneration, and Alzheimer's disease with TDP‐43 pathology. This study reports that wild‐type PDI slows down phase separation of TDP‐43 through direct interaction with TDP‐43.
Jia‐Qi Liu, Hao Liu, Yu‐Xuan Sun, Yuying Li, Xiangyi Liu, Li‐Qiang Wang, Zhaofei Yang, Qi Fu, Xiaojiao Xu, Jie Chen, Yingshuang Zhang, Jun Zhou, Weidong Le, Mengchao Cui, Yi Liang   +14 more
wiley   +1 more source

Plasmonic glyco-nanoparticles for single-test multiplexed detection and differentiation of cancer cells.

Nanoscale
Ullah AKMA, Juhong A, Ramadan S, Yang CW, Qiu Z, Huang X.   +5 more
europepmc   +1 more source

Clinical characteristics and risk factors of necrotizing pneumonia secondary to severe pneumonia in children. [PDF]

Front Pediatr
Che L, Zhou W, Chen Q, Cheng F, Tian J.
europepmc   +1 more source

Development of novel monoclonal antibodies for detection of pan-Lassa virus. [PDF]

PLoS Negl Trop Dis
Paroha R, Saito T, Yamada S, Click C, Paessler S, Maruyama J.   +5 more
europepmc   +1 more source

Characterizing Multifunctional Mesoporous Cerium Silicate Nanoparticles for Potential Use in Bioactive Dental Materials: A Proof-of-Concept Study. [PDF]

Materials (Basel)
Jones RS, Singh T, Mutreja I, Kumar D.
europepmc   +1 more source

Extracellular vesicles as biomarkers of disease progression and therapeutic response in patients with spinal muscular atrophy. [PDF]

Mol Ther Adv
Poulin KL, René CA, Smith IC, Vacratsis PO, Burger D, McMillan HJ, Kothary R, Perkins TJ, Warman-Chardon J, Parks RJ.   +9 more
europepmc   +1 more source

Life-Threatening Necrotizing Pneumonia in a Pediatric Patient: A Complicated Case From Palestine. [PDF]

Case Rep Pediatr
Abu-Hijleh H, Kawa N, Alhmam SA, Swafta K, Alawneh M, Saymeh A, Adas A.   +6 more
europepmc   +1 more source

Dopamine drives persistent remodelling of the maternal brain. [PDF]

Nature
O'Chan JC, Di Salvo G, Cunningham AM, Dutta S, Brindley E, Weekley BH, Chen W, Iyer RR, Wan E, Zhang C, Mechawar N, Turecki G, Maze I.   +12 more
europepmc   +1 more source

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Neuroprotective potential of Cilostazol in 3-NP provoked Huntington's disease-associated symptoms

Research Journal of Pharmacy and Technology, 2021
Huntington's disease (HD), a neurodegenerative condition specified by mitochondrial deficits, psychiatric and cognitive impairment developed due to neuronal damage in the brain. 3-nitropropionic acid (3-NP), an inhibitor of succinate dehydrogenase develops behavioral, biochemical as well as histological alterations in the striatal region of brain ...
Surbhi Gupta, Bhupesh Sharma
openaire   +1 more source

Characteristic Changes of Astrocyte and Microglia in Rat Striatum Induced by 3-NP and MCAO

Neurochemical Research, 2015
Our previous studies had confirmed that both 3-NP and MCAO induced the behavioral defect as well as striatal neuronal injury and loss in experimental rats. This study aimed to examine different response forms of striatal astrocyte and microglia in 3-NP and MCAO rat models.
Shuhua, Mu, Bingbing, Liu, Lisi, Ouyang, Mali, Zhan, Si, Chen, Jiajia, Wu, Jiachang, Chen, Xianyou, Wei, Weiping, Wang, Jian, Zhang, Wanlong, Lei   +10 more
openaire   +2 more sources