Results 271 to 280 of about 17,169,589 (293)

Neuroprotective Effect of Boswellia serrata against 3-NP Induced Experimental Huntington’s Disease

Current Bioactive Compounds
Objectives: The study aimed to assess the neuroprotective effect of Boswellia serrata against 3-NP-induced experimental Huntington’s disease. Background: Previous studies have shown Boswellia to have sedative, analgesic, and anti-tumour effects. Boswellia serrata yields four pentacyclic triterpene acids and boswellic acid, a bioactive substance that
Vinay Kumar, Chanchal Sharma, Mohamad Taleuzzaman, Kandasamy Nagarajan, Anzarul Haque, Mamta Bhatia, Sumayya Khan, Mohamad Ayman Salkini, Pankaj Bhatt   +8 more
openaire   +1 more source

Conserved structures among the nucleocapsid proteins of the paramyxoviridae: Complete nucleotide sequence of human parainfluenza virus type 3 NP mRNA

Virology, 1986
The nucleotide sequence of the mRNA coding for the nucleocapsid protein (NP) of the paramyxovirus, human parainfluenza virus type 3 (PIV-3), has been determined. The NP mRNA was found to contain 1642 bases, excluding poly(A), and encode a protein of 515 amino acids, with a molecular weight of 57,823.
A, Sánchez, A K, Banerjee, Y, Furuichi, M A, Richardson   +3 more
openaire   +2 more sources

Syntheses and characterization of thallium(I) complexes with 3-nitrophenoxide [Tl(3-np)], 4-nitrobenzoate [Tl(4-nb)] and 2,4-dinitrophenoxide [Tl(2,4-dnp)]: X-ray crystal structures of [Tl(3-np)]n and Tl(2,4-dnp) (two new polymeric compounds)

Polyhedron, 2002
Abstract Complexes thallium(I)3-nitrophenoxide [Tl(3-np)], thallium(I)2,4-dinitrophenoxide [Tl(2,4-dnp)] and thallium(I)4-nitrobenzoate [Tl(4-nb)] have been synthesized using a direct reaction between TlNO 3 and the appropriate ligand. The complexes have been isolated and characterized by IR spectra and CHN elemental analyses.
Ali R Mahjoub, Ali Morsali, Hossian Bagherzadeh   +2 more
openaire   +1 more source

Antioxidant and antiapoptotic actions of selegiline protect against 3-NP-induced neurotoxicity in rats.

Naunyn-Schmiedeberg's archives of pharmacology, 2018
The present study was designed to investigate the neuroprotective effect of selegiline on 3-nitropropionic acid (3-NP)-induced neurotoxicity. Selegiline was intraperitoneally injected at doses 2.5, 5, and 10 mg/kg, 3 days prior to and continued daily, 30 min before 3-NP administration. 3-NP (20 mg/kg, i.p.) was administered for four consecutive days. 3-
Sara A, Wahdan, Mariane G, Tadros, Amani E, Khalifa   +2 more
openaire   +1 more source

Succinobucol versus probucol: Higher efficiency of succinobucol in mitigating 3-NP-induced brain mitochondrial dysfunction and oxidative stress in vitro

Mitochondrion, 2013
This study evaluated and compared the potential protective effects of probucol and succinobucol, two lipid-lowering compounds with anti-inflammatory and antioxidant properties, on oxidative stress and mitochondrial dysfunction induced by 3-nitropropionic acid (3-NP, a succinate dehydrogenase (SDH) inhibitor largely used as model of Huntington's disease)
Dirleise, Colle, Danúbia B, Santos, Juliana M, Hartwig, Marcelo, Godoi, Antonio L, Braga, Marcelo, Farina   +5 more
openaire   +2 more sources

Cr(OH)3-NPs-CNC hybrid nanocomposite: a sorbent for adsorptive removal of methylene blue and malachite green from solutions

Environmental Science and Pollution Research, 2017
In this article, Cr(OH)3 nanoparticle-modified cellulose nanocrystal (CNC) as a novel hybrid nanocomposite (Cr(OH)3-NPs-CNC) was prepared by a simple procedure and used as a sorbent for adsorptive removal of methylene blue (MB) and malachite green (MG) from aqueous solution.
Farzin Nekouei, Shahram Nekouei, Farzaneh Keshtpour, Hossein Noorizadeh, Shaobin Wang   +4 more
openaire   +3 more sources

ADIOL protects against 3-NP-induced neurotoxicity in rats: Possible impact of its anti-oxidant, anti-inflammatory and anti-apoptotic actions

Progress in Neuro-Psychopharmacology and Biological Psychiatry, 2015
Huntington's disease (HD) is a progressive neurodegenerative disorder with a wide spectrum of cognitive, behavioral and motor abnormalities. The mitochondrial toxin 3-nitropropionic acid (3-NP) effectively induces specific behavioral changes and selective striatal lesions similar to that observed in HD.
Diana M F, Hanna, Mariane G, Tadros, Amani E, Khalifa   +2 more
openaire   +2 more sources

Crystal Structure of Double Co(NH3)6 3 + Np(V) Malonates Co(NH3)6(NpO2C3H2O4)2A·H2O (A = OH and NO3)

Radiochemistry, 2004
X-ray diffraction analysis of Co(NH3)6(NpO2C3H2O4)2NO3·H2O (I) and Co(NH3)6(NpO2· C3H2O4)2OH·H2O (II) showed that they consist of [NpO2C3H2O4] n n - infinite anionic chains, [Co(NH3)6]3 + cations, NO3 - (I) and OH- (II) anions, and molecules of crystallization water. The anionic chain
I. A. Charushnikova, N. N. Krot, I. N. Polyakova   +2 more
openaire   +1 more source

Potential role of TrkB agonist in neuronal survival by promoting CREB/BDNF and PI3K/Akt signaling in vitro and in vivo model of 3-nitropropionic acid (3-NP)-induced neuronal death

Apoptosis, 2020
Sahabuddin Ahmed, M. Kwatra, Basveshwar Gawali, S. R. Panda, V. Naidu   +4 more
semanticscholar   +1 more source

Neuroprotective Effect of Capsaicin In 3-NP Induced Cognitive, Oxidative and Mitochondrial Impairment In Animal Model Of Huntington’s Disease

African Journal of Biomedical Research
The study objectives are to investigate the effect of capsaicin on cognitive impairments, mitochondrial deficits, and oxidative insults induced by 3-nitro propanoic acid (3-NP) in a rodent model of Huntington’s disease.
Sakshi Tyagi, Nikhila Shekhar
openaire   +1 more source