Results 51 to 60 of about 19,358,422 (205)

NP-ПОЛНОТА В СИЛЬНОМ СМЫСЛЕ ЗАДАЧИ «3-РАЗБИЕНИЕ ПРОИЗВЕДЕНИЯ»

Informatika, 2018
Доказывается NP-полнота в сильном смысле задачи 3-РАЗБИЕНИЕ ПРОИЗВЕДЕНИЯ.В этой задаче дано множество из 3m элементов A={a1, a2, …, a3m} и для каждого элемента ai дан его размер s(ai)∈Z+.

doaj  

Extraction of Silicon-Containing Nanoparticles from an Agricultural Soil for Analysis by Single Particle Sector Field and Time-of-Flight Inductively Coupled Plasma Mass Spectrometry

Nanomaterials, 2023
The increased use of silica and silicon-containing nanoparticles (Si-NP) in agricultural applications has stimulated interest in determining their potential migration in the environment and their uptake by living organisms.
Zhizhong Li, Madjid Hadioui, Kevin J. Wilkinson   +2 more
doaj   +1 more source

Role of surface charge and oxidative stress in cytotoxicity of organic monolayer-coated silicon nanoparticles towards macrophage NR8383 cells

Particle and Fibre Toxicology, 2010
Background Surface charge and oxidative stress are often hypothesized to be important factors in cytotoxicity of nanoparticles. However, the role of these factors is not well understood.
Bhattacharjee Sourav, de Haan Laura HJ, Evers Nynke M, Jiang Xue, Marcelis Antonius TM, Zuilhof Han, Rietjens Ivonne MCM, Alink Gerrit M   +7 more
doaj   +1 more source

Complement Receptor 3 Pathway and NMDA Receptor 2B Subunit Involve Neuropathic Pain Associated with Spinal Cord Injury

Journal of Pain Research, 2022
Yong Li,1,* Sheng-Chun Fang,2,* Lan Zhou,1 Xue-Mei Mo,3 Hao-Dong Guo,3 Yan-Bo Deng,3 Hong-Hao Yu,1 Wei-Yi Gong3 1College of Biotechnology, Guilin Medical University, Guilin, Guangxi, 541100, People’s Republic of China; 2Department of ...
Li Y, Fang SC, Zhou L, Mo XM, Guo HD, Deng YB, Yu HH, Gong WY   +7 more
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Probucol increases striatal glutathione peroxidase activity and protects against 3-nitropropionic acid-induced pro-oxidative damage in rats. [PDF]

PLoS ONE, 2013
Huntington's disease (HD) is an autosomal dominantly inherited neurodegenerative disease characterized by symptoms attributable to the death of striatal and cortical neurons.
Dirleise Colle, Danúbia Bonfanti Santos, Eduardo Luiz Gasnhar Moreira, Juliana Montagna Hartwig, Alessandra Antunes dos Santos, Luciana Teixeira Zimmermann, Mariana Appel Hort, Marcelo Farina   +7 more
doaj   +1 more source

Utilizing targeted gene therapy with nanoparticles binding alpha v beta 3 for imaging and treating choroidal neovascularization.

PLoS ONE, 2011
PurposeThe integrin αvβ3 is differentially expressed on neovascular endothelial cells. We investigated whether a novel intravenously injectable αvβ3 integrin-ligand coupled nanoparticle (NP) can target choroidal neovascular membranes (CNV) for imaging ...
Hani Salehi-Had, Mi In Roh, Andrea Giani, Toshio Hisatomi, Shintaro Nakao, Ivana K Kim, Evangelos S Gragoudas, Demetrios Vavvas, Samira Guccione, Joan W Miller   +9 more
doaj   +1 more source

Proactive transplantation of human neural stem cells prevents degeneration of striatal neurons in a rat model of Huntington disease

Neurobiology of Disease, 2004
We have investigated the effectiveness of transplantation of human neural stem cells into adult rat striatum prior to induction of striatal damage with the mitochondrial toxin 3-nitropropionic acid (3-NP).
Jae K Ryu, Jean Kim, Sung J Cho, Kozo Hatori, Astushi Nagai, Hyun B Choi, Min C Lee, James G McLarnon, Seung U Kim   +8 more
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Mice Deficient in Cellular Glutathione Peroxidase Show Increased Vulnerability to Malonate, 3-Nitropropionic Acid, and 1-Methyl-4-Phenyl-1,2,5,6-Tetrahydropyridine

Journal of Neuroscience, 2000
Glutathione peroxidase (GSHPx) is a critical intracellular enzyme involved in detoxification of hydrogen peroxide (H2O2) to water. In the present study we examined the susceptibility of mice with a disruption of the glutathione peroxidase gene to the ...
P. Klivényi, Ole A. Andreassen, R. Ferrante, A. Dedeoglu, Gerald Mueller, E. Lancelot, M. Bogdanov, Julie K. Andersen, D. Jiang, M. Beal   +9 more
semanticscholar   +1 more source

Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid

Journal of Neuroscience, 1993
An impairment of energy metabolism may underlie slow excitotoxic neuronal death in neurodegenerative diseases. We therefore examined the effects of intrastriatal, subacute systemic, or chronic systemic administration of the mitochondrial toxin 3 ...
M. Beal, E. Brouillet, B. Jenkins, R. Ferrante, N. Kowall, Joanne M. Miller, E. Storey, R. Srivastava, B. Rosen, B. Hyman   +9 more
semanticscholar   +1 more source

m6A-binding protein YTHDF2 alleviates 3-nitropropionic acid–induced mitochondrial dysfunction of goat granulosa cells

Ecotoxicology and Environmental Safety
3-Nitropropionic acid (3-NP), a mitochondrial complex II inhibitor and prevalent environmental contaminant, has been implicated in female reproductive toxicity, yet its underlying epigenetic mechanisms remain largely unclear.
Dongxu Li, Minghui Zhu, Wenyue Yu, Zhixuan Zhou, Jingwen Wang, Dongyan Liu, Dagan Mao, Feng Wang, Yongjie Wan   +8 more
doaj   +1 more source