Results 81 to 90 of about 13,770,514 (290)
NP-completeness of Bipartite Exact Cut
, 2019 \textsc{Max-Cut} is a well-known NP-complete problem in which, given a graph $G$ and an integer $k$, one needs to determine whether there exists a cut of size at least $k$ in $G$. An exact version is likewise asking whether $G$ has a cut of size exactly $
Thinh D. Nguyen (6385907)
core +1 more source
PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines
FEBS Open Bio, EarlyView.Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart +7 more
wiley +1 more source
FEBS Open Bio, EarlyView.Amino acids sequence of two different proteins with the same sequence (chameleon sequence—black boxes) represent in 3D structure of the proteins different secondary structures: HHHH—helical and BBB—Beta‐structural. The chains folded in water environment adopt different III‐order structures in which the chameleon fragments appear to adopt similar status
Irena Roterman +4 more
wiley +1 more source
PLoS ONE, 2011 PurposeThe integrin αvβ3 is differentially expressed on neovascular endothelial cells. We investigated whether a novel intravenously injectable αvβ3 integrin-ligand coupled nanoparticle (NP) can target choroidal neovascular membranes (CNV) for imaging ...
Hani Salehi-Had +9 more
doaj +1 more source
The FASEB Journal, 2009 The 3‐nitropropionic acid model Of Huntington's disease produces a variety of biochemical anomalies. One of these, is the activation of the protease calpain. Excess calpain activity is probably responsible for major cell death expressed as striatial degeneration.
Leo Kesner +5 more
openaire +1 more source
Exploiting structure to cope with NP-hard graph problems: Polynomial and exponential time exact algorithms [PDF]
, 2010 An ideal algorithm for solving a particular problem always finds an optimal solution, finds such a solution for every possible instance, and finds it in polynomial time.
VAN-'T-HOF, PIM
core
Development of human monoclonal antibodies against TARM1 by yeast display
FEBS Open Bio, EarlyView.Human monoclonal antibodies against TARM1 are generated by yeast display‐guided selection. These antibodies bind to soluble and cell‐surface forms of TARM1. Also, these antibodies exhibit agonistic activity in the NFAT‐GFP reporter assay, indicating that TARM1 signaling can be functionally modulated by antibodies and suggesting TARM1 as a potential ...
Rikio Yabe +5 more
wiley +1 more source
Neurobiology of Disease, 2004 We have investigated the effectiveness of transplantation of human neural stem cells into adult rat striatum prior to induction of striatal damage with the mitochondrial toxin 3-nitropropionic acid (3-NP).
Jae K Ryu +8 more
doaj +1 more source
, 2018 A) rE proteins from all serotypes were individually adsorbed to the PLGA nanoparticles in variable srE/NP (w/w%) ratios. Adsorption efficiency was determined by the amount of non-adsorbed rE after the spinning down the particles.
Ashlie Thomas (5049497) +10 more
core +1 more source
FEBS Open Bio, EarlyView.14‐day casting‐induced immobilization reduced gastrocnemius muscle mass and increased non‐heme iron and ferritin heavy chain levels. Despite iron accumulation, transferrin receptor 1 and iron regulatory protein 2 were paradoxically upregulated. Lipid peroxidation was elevated without compensatory antioxidant responses.
Haruka Yokogawa +2 more
wiley +1 more source