Results 71 to 80 of about 422,853 (267)
On the Annihilators of Derivations with Engel Conditions in Prime Rings [PDF]
, 2012 [[abstract]]Let R be a prime ring of char R 6= 2, d a non-zero derivation of R, 0 6= b 2 R and a non-zero right ideal of R such that b[[d(x); x]n; [y; d(y)]m] = 0 for all x; y 2 , where n;m 0 are xed integers.
R. K. Sharma, B. Dhara
core
Molecular Oncology, EarlyView.Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
Molecular Oncology, EarlyView.CIN85 is highly expressed in osteosarcoma, particularly in metastatic lesions. Its overexpression increases cell migration and Matrigel invasion, while silencing CIN85 suppresses these behaviors. Transcriptome analysis shows that CIN85 regulates MMP2, COL3A1, and Akt/mTOR signaling. Targeting these pathways reverses CIN85‐induced motility, highlighting
Iryna Horak +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena +15 more
wiley +1 more source
Interpreting the effects of DNA polymerase variants at the structural level
Molecular Oncology, EarlyView.Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi +7 more
wiley +1 more source
Derivations on One-Sided Ideals of Prime Rings [PDF]
, 2015 [[abstract]]Let R be a prime ring, ρ a nonzero right ideal of R, d a derivation of R and n a fixed positive integer.(I) If d(u)u^n=0 for all u belong to ρ, then d(ρ)ρ=0.(II) If {u^n}d(u)=0 for all u belong to ρ, then d=0 unless R isomorphic to M_2(F ...
林裕清 +3 more
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On Generalized (Sigma,Tau)-Derivations in 3-Prime Near-Rings
Tamkang Journal of Mathematics, 2020 Let N be a 3-prime left near-ring with multiplicative center Z, f be a generalized (σ,τ)- derivation on N with associated (σ,τ)-derivation d and I be a semigroup ideal of N. We proved that N must be a commutative ring if f(I)⊂Z or f act as a homomorphism or f act as an anti-homomorphism.
openaire +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
On Classical Prime Near-ring Modules [PDF]
In 2005, M. Behboodi introduced the notion of a classical prime ring module, which he showed is, in general, nonequivalent to a (Dauns) prime ring module. In this paper, we extended the idea of classical primeness to near-ring module.
Juglal, S., Djagba, P.
core +1 more source
Minimal prime ideals of skew polynomial rings and near pseudo-valuation rings [PDF]
, 2013 summary:Let $R$ be a ring. We recall that $R$ is called a near pseudo-valuation ring if every minimal prime ideal of $R$ is strongly prime. Let now $\sigma $ be an automorphism of $R$ and $\delta $ a $\sigma $-derivation of $R$. Then $R$ is said to be an
Bhat, Vijay Kumar
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