Results 91 to 100 of about 8,871,631 (366)

The Wind Momentum-Luminosity relationship: blue supergiants in the spiral galaxy NGC 300 [PDF]

open access: yesarXiv, 2002
We have carried out the wind analysis of six A-type supergiants in NGC 300. The derived Wind Momentum-Luminosity Relationship is compared with that of Galactic and M31 blue supergiants and with theoretical models.
arxiv  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Book Review: Heiduk, Felix (ed.): Security Sector Reform in Southeast Asia: From Policy to Practice

open access: yesJournal of Current Southeast Asian Affairs, 2015
Book Review of the edited volume by Heiduk, Felix (ed.) (2014), Security Sector Reform in Southeast Asia: From Policy to Practice. Basingstoke, Hampshire: Palgrave MacMillan, ISBN 978-0-230-22 896-2, 264 pages.
Leanne-Marie McCarthy-Cotter
doaj  

Small $P_{\perp}^2$ Elastic Proton-Proton Polarization near 300 GeV [PDF]

open access: yesarXiv, 1996
Using two hopefully reasonable assumptions plus existing data on the analyzing power in high energy proton-proton elastic scattering, we estimate that the hadronic helicity-flip amplitude at $P^2_{\perp}$ of 0.003 (GeV/c)$^2$ is neglible near 300 GeV. This would allow the absolute calibration of a CNI polarimeter.
arxiv  

The atypical KRASQ22K mutation directs TGF‐β response towards partial epithelial‐to‐mesenchymal transition in patient‐derived colorectal cancer tumoroids

open access: yesMolecular Oncology, EarlyView.
TGF‐β has a complex role in cancer, exhibiting both tumor‐suppressive and tumor‐promoting properties. Using a series of differentiated tumoroids, derived from different stages and mutational background of colorectal cancer patients, we replicate this duality of TGF‐β in vitro. Notably, the atypical but highly aggressive KRASQ22K mutation rendered early‐
Theresia Mair   +17 more
wiley   +1 more source

Quality of Different Scales in an Online Survey in Mexico and Colombia

open access: yesJournal of Politics in Latin America, 2015
The formulation of theories and hypotheses is done at the level of concepts. These concepts are often tested by operationalizing them using survey questions.
Melanie Revilla, Carlos Ochoa
doaj  

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

Book Review: Jandl, Thomas, Vietnam in the Global Economy – The Dy-namics of Integration, Decentralization and Contested Politics

open access: yesJournal of Current Southeast Asian Affairs, 2014
Book Review of the Monograph: Thomas Jandl (2013), Vietnam in the Global Economy – The Dynamics of Integration, Decentralization and Contested Politics.
Adam Fforde
doaj  

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

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