Results 101 to 110 of about 3,137,133 (371)

Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM

open access: yesMolecular Oncology, EarlyView.
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak   +14 more
wiley   +1 more source

Myanmar on the Move: An Overview of Recent Developments

open access: yesJournal of Current Southeast Asian Affairs, 2012
This paper examines the remarkable political transition underway in Myanmar/Burma since the inauguration of President Thein Sein at the end of March 2011.
Lex Rieffel
doaj  

Stretching Vibrations of C-Br in P-Dibromobenzene Nanoparticles [PDF]

open access: yesarXiv, 2009
Raman spectrums of nanoparticles of a p-dibromobenzene with size of 300 nanometers and 50 nanometers are measured. It is found that frequencies of lines of stretching vibrations of C-Br at reduction of the sizes of nanoparticles below 300 nanometers are incremented.
arxiv  

Enhancement of CO2 Adsorption and Catalytic Properties by Fe-Doping of [Ga2(OH)2(L)] (H4L = Biphenyl-3,3′,5,5′-tetracarboxylic Acid), MFM-300(Ga2)

open access: yesInorganic Chemistry, 2016
Metal–organic frameworks (MOFs) are usually synthesized using a single type of metal ion, and MOFs containing mixtures of different metal ions are of great interest and represent a methodology to enhance and tune materials properties.
C. P. Krap   +18 more
semanticscholar   +1 more source

Targeting the MDM2‐MDM4 interaction interface reveals an otherwise therapeutically active wild‐type p53 in colorectal cancer

open access: yesMolecular Oncology, EarlyView.
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini   +10 more
wiley   +1 more source

Reaching across the Mekong: Local Socioeconomic and Gender Effects of Lao-Thai Crossborder Linkages

open access: yesJournal of Current Southeast Asian Affairs, 2011
Following trade agreements between ASEAN states, the expansion of cross-border roads and bridges between Laos and Thailand has linked local communities and distant markets in increasingly diverse ways. Although the planned impacts of such integration are
José Edgardo Gomez, Jr.   +3 more
doaj  

Highly multiplexed digital PCR assay for simultaneous quantification of variant allele frequencies and copy number alterations of KRAS and GNAS in pancreatic cancer precursors

open access: yesMolecular Oncology, EarlyView.
Combining melting curve analysis enhances the multiplexing capability of digital PCR. Here, we developed a 14‐plex assay to simultaneously measure single nucleotide mutations and amplifications of KRAS and GNAS, which are common driver genes in pancreatic cancer precursors. This assay accurately quantified variant allele frequencies in clinical samples
Junko Tanaka   +10 more
wiley   +1 more source

Malapportionment and Geographical Bases of Electoral Support in the Brazilian Senate Desproporcionalidade de Representação e Geografia de Bases Eleitorais no Senado Brasileiro

open access: yesJournal of Politics in Latin America, 2013
This paper analyzes the relationship between malapportionment and electoral bases of support for Brazilian senators. The conventional wisdom asserts that malapportionment contributes to the “politics of backwardness” – that it facilitates clientelism and
Taeko Hiroi, Pedro Neiva
doaj  

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