Results 11 to 20 of about 755,225 (262)

Additional file 1 of Gene expression profiling unveils the temporal dynamics of CIGB-300-regulated transcriptome in AML cell lines

, 2023
Additional file 1: Figure S1. Diagnostic plots in control cells or CIGB-300 treated OCI-AML3 (O) and HL-60 (H) samples for 3h and 30min. (A) One dimensional hierarchical clustering of all samples (replicates 1, 2, 3), (B) ANOVA R-squared (^2) of ...
Ailenis Rosales (16487109), Mauro Rosales (9761930), Yasser Perera (2263075), Daniel Palenzuela (16487112), George V. Pérez (12227858), Dania Vázquez-Blomquist (16487103), Ailyn C. Ramón (16487106), Silvio E. Perea (1798564)   +7 more
core   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

PowerTAC 2015-1 Trial 271-300

, 2015
<p>Log and boot files of games 271 - 300</p ...
PowerTAC, PowerTAC (5191558)
core   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

300-word project description of Five Elements of Living Treasure

, 2019
A 300-word overview of the reserach and development of the multimedia composition and performance, Five Elements of Living Treasure.
Insook Choi (7390499)
core   +1 more source

Assessing the activity of ETC inhibitors against ELQ-300-resistant T. gondii parasites.

, 2023
(A-I) Dose-response curves depicting the percent proliferation of ELQ-300-resistant (ELQR, blue) T. gondii parasites, or the corresponding ELQ-300-sensitive parental strain (ELQS, black), in the presence of increasing concentrations of (A) ELQ-300, (B ...
Esther Rajendran (6321464), Rachel A. Leonard (5195411), Christina Spry (284689), F. Victor Makota (16625292), Laura Shuttleworth (16625295), Jenni A. Hayward (10063377), Ursula Wiedemann (16625298), Kevin J. Saliba (284698), Giel G. van Dooren (10063383), Alexander G. Maier (3955484), Daniela Cihalova (468074), Soraya M. Zwahlen (10063380)   +11 more
core   +1 more source

Myanmar’s China Policy since 2011: Determinants and Directions

Journal of Current Southeast Asian Affairs, 2015
This paper argues that a key factor in Myanmar’s new approach towards China since 2011 has been the Myanmar government’s foreign policy goal to reintegrate itself into the international community. The success of this approach is dependent on Myanmarâ€
Maung Aung Myoe
doaj  

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

FEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes, Jan Brysch, Carmen Gelze, Lilli Meier, Daniel Kümmel   +4 more
wiley   +1 more source

Too Undisciplined to Legislate? Party Unity and Policy-making in Brazil Demasiado indisciplinados para gobernar? Unidad partidaria y elaboración de políticas en Brasil

Journal of Politics in Latin America, 2012
Discipline and cohesiveness of political parties are essential for legislatures to engage in policy-making. Parties in Brazil have historically been considered ideologically weak and uninvolved in policy issues of national importance.
Sylvia Gaylord
doaj