Results 21 to 30 of about 11,467,373 (235)

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

Table3_CIGB-300-Regulated Proteome Reveals Common and Tailored Response Patterns of AML Cells to CK2 Inhibition.XLSX

, 2022
Protein kinase CK2 is a highly pleiotropic and ubiquitously expressed Ser/Thr kinase with instrumental roles in normal and pathological states, including neoplastic phenotype in solid tumor and hematological malignancies.
Yassel Ramos (1974889), Katharina Zettl (12227864), Jacek R. Wiśniewski (23900), Mauro Rosales (9761930), Arielis Rodríguez-Ulloa (12227855), Ke Yang (192709), Yasser Perera (2263075), George V. Pérez (12227858), Luis J. González (2641525), Thalia Soto (12227861), Vladimir Besada (1974907), Silvio E. Perea (1798564)   +11 more
core   +1 more source

Punjabi 300 : Sukhwant Hundal

, 2013
Raw footage for "Punjabi 300: The Komagata Maru - A Continuing Journey." This interview brings in Sukhwant Hundal's perspective on the Komagata Maru incident.Arts, Faculty ofAsian Studies, Department ...
Gedda, Peder, Joshi, Abhijeet, Dhaliwal, Satinder, Ghuman, Jushin, Attri, Prateek   +4 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Assessing the activity of ETC inhibitors against ELQ-300-resistant T. gondii parasites.

, 2023
(A-I) Dose-response curves depicting the percent proliferation of ELQ-300-resistant (ELQR, blue) T. gondii parasites, or the corresponding ELQ-300-sensitive parental strain (ELQS, black), in the presence of increasing concentrations of (A) ELQ-300, (B ...
Esther Rajendran (6321464), Rachel A. Leonard (5195411), Christina Spry (284689), F. Victor Makota (16625292), Laura Shuttleworth (16625295), Jenni A. Hayward (10063377), Ursula Wiedemann (16625298), Kevin J. Saliba (284698), Giel G. van Dooren (10063383), Alexander G. Maier (3955484), Daniela Cihalova (468074), Soraya M. Zwahlen (10063380)   +11 more
core   +1 more source

Punjabi 300 : Barj Dhahan

, 2013
Raw footage for "Punjabi 300: The Komagata Maru - A Continuing Journey." This interview brings in Barj Dhahan's perspective on the Komagata Maru incident.Arts, Faculty ofAsian Studies, Department ...
Gedda, Peder, Joshi, Abhijeet, Dhaliwal, Satinder, Ghuman, Jushin, Attri, Prateek   +4 more
core   +1 more source

Myanmar’s China Policy since 2011: Determinants and Directions

Journal of Current Southeast Asian Affairs, 2015
This paper argues that a key factor in Myanmar’s new approach towards China since 2011 has been the Myanmar government’s foreign policy goal to reintegrate itself into the international community. The success of this approach is dependent on Myanmarâ€
Maung Aung Myoe
doaj  

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

ELQ-300-resistant parasites exhibit cross-resistance to MMV688853 in O₂ consumption rate activity assays.

, 2023
(A-C) Dose-response curves depicting the OCR of intact WT (black) or atovaquone-resistant (ATVR, red) T. gondii parasites in the presence of increasing concentrations of (A) atovaquone, (B) ELQ-300 or (C) MMV688853.
Esther Rajendran (6321464), Rachel A. Leonard (5195411), Christina Spry (284689), F. Victor Makota (16625292), Laura Shuttleworth (16625295), Jenni A. Hayward (10063377), Ursula Wiedemann (16625298), Kevin J. Saliba (284698), Giel G. van Dooren (10063383), Alexander G. Maier (3955484), Daniela Cihalova (468074), Soraya M. Zwahlen (10063380)   +11 more
core   +1 more source

Punjabi 300 : Ajmer Rode

, 2013
Raw footage for "Punjabi 300: The Komagata Maru - A Continuing Journey." This interview brings in Ajmer Rode's perspective on the Komagata Maru incident.Arts, Faculty ofAsian Studies, Department ...
Rode, Ajmer, Gedda, Peder, Joshi, Abhijeet, Dhaliwal, Satinder, Ghuman, Jushin, Attri, Prateek   +5 more
core   +1 more source