Results 21 to 30 of about 755,225 (262)
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
PowerTAC 2015-04 Qualifying 296-300
, 2015 <p>Log and boot files of games 296 - 300</p ...
PowerTAC, PowerTAC (5191558)
core +1 more source
Journal of Politics in Latin America, 2012 Do Latin American citizens share a common conception of the ideological left–right distinction? And if so, is this conception linked to individuals’ ideological self-placement?
Nina Wiesehomeier, David Doyle
doaj
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Journal of Current Southeast Asian Affairs, 2015 A modern conception of oligarchy, which can be housed under an authoritarian regime as easily as it can under a liberal democratic one, can affect our understanding of the potential national political repercussions of extreme inequalities of wealth. This
T. F. Rhoden
doaj
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source
Journal of Politics in Latin America, 2013 Since the return to democracy, Uruguayan presidents have built cabinets of varying natures (majority and minority coalitions, majority and minority parties).
Daniel Chasquetti
doaj
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
AMČR - dokument C-200912982M-DT-300
, 2008 Stav: 3Označení: DR-12982-5559Popis: Mezi sektory C a F obj.
https://api.aiscr.cz/id/ORG-000094 +1 more
core +1 more source
Myanmar in Contemporary Chinese Foreign Policy – Strengthening Common Ground, Managing Differences
Journal of Current Southeast Asian Affairs, 2012 This assessment first briefly examines recent features of China’s approach to foreign affairs, and then examines in greater detail features in China’s approach to relations with its neighbours, especially in Southeast Asia. It does so in order to discern
Robert Sutter
doaj