Correction: Sadler et al. Lipid Metabolism Is Dysregulated in the Motor Cortex White Matter in Amyotrophic Lateral Sclerosis. Metabolites 2022, 12, 554 [PDF]
MetabolitesIn the original publication [...]
Gemma L. Sadler +8 more
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Baseline tumour burden and prognosis in breast cancer treated with immune checkpoint inhibitors [PDF]
BreastBackground: Immune checkpoint inhibitors (ICI), alone or in combination with other agents, are now standard of care for a range of tumour types, including breast cancer. Radiological assessment of baseline tumour burden has been associated with prognosis
Julia Dixon-Douglas +7 more
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Concussion, 2022 Aim: To pilot a modification of the Post Concussion Symptom Inventory, the Melbourne Paediatric Concussion Scale (MPCS) and examine its clinical utility.
Gavin A Davis +13 more
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Phosphodiesterase-4 inhibition alters gene expression and improves isoniazid-mediated clearance of Mycobacterium tuberculosis in rabbit lungs. [PDF]
PLoS Pathogens, 2011 Tuberculosis (TB) treatment is hampered by the long duration of antibiotic therapy required to achieve cure. This indolent response has been partly attributed to the ability of subpopulations of less metabolically active Mycobacterium tuberculosis (Mtb ...
Selvakumar Subbian +9 more
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Evaluating Functional Immunity Following Encapsulated Bacterial Infection and Vaccination
Vaccines, 2021 Encapsulated bacteria such as Streptococcus pneumoniae, Haemophilus influenzae type b and Neisseria meningitidis cause significant morbidity and mortality in young children despite the availability of vaccines.
Zheng Quan Toh +7 more
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Phosphodiesterase 4 inhibition reduces innate immunity and improves isoniazid clearance of Mycobacterium tuberculosis in the lungs of infected mice. [PDF]
PLoS ONE, 2011 Tuberculosis (TB) caused by Mycobacterium tuberculosis (Mtb) is one of the leading infectious disease causes of morbidity and mortality worldwide. Though current antibiotic regimens can cure the disease, treatment requires at least six months of drug ...
Mi-Sun Koo +10 more
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Aerosol Delivery of Palivizumab in a Neonatal Lamb Model of Respiratory Syncytial Virus Infection
Viruses, 2023 (1) Background: Palivizumab has been an approved preventative monoclonal antibody for respiratory syncytial virus (RSV) infection for over two decades. However, due to its high cost and requirement for multiple intramuscular injections, its use has been ...
Hasindu S. Edirisinghe +10 more
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F1000Research, 2023 Cancer is driven by mutations of the genome that can result in the activation of oncogenes or repression of tumour suppressor genes. In acute lymphoblastic leukemia (ALL) focal deletions in IKAROS family zinc finger 1 (IKZF1) result in the loss of zinc ...
Andrew Lonsdale +5 more
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Toxins, 2021 Venoms are complex mixtures of biologically active molecules that impact multiple physiological systems. Manufacture of antivenoms (AVs) therefore requires potency testing using in vivo models to ensure AV efficacy. As part of ongoing research to replace
Erin E. Verity +4 more
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Metals, 2020 Metal content determination is one of the critical aspects of preparing electronic waste for metal recycling. In spite of the fact that end-of-life printed circuit boards are considered to be a secondary resource reservoir, no standard procedure exists ...
Dagmar Remeteiová +4 more
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