Results 11 to 20 of about 94,503 (212)
Cancer is driven by mutations of the genome that can result in the activation of oncogenes or repression of tumour suppressor genes. In acute lymphoblastic leukemia (ALL) focal deletions in IKAROS family zinc finger 1 (IKZF1) result in the loss of zinc ...
Andrew Lonsdale +5 more
doaj +1 more source
Venoms are complex mixtures of biologically active molecules that impact multiple physiological systems. Manufacture of antivenoms (AVs) therefore requires potency testing using in vivo models to ensure AV efficacy. As part of ongoing research to replace
Erin E. Verity +4 more
doaj +1 more source
Spoken Expressive Vocabulary in 2-Year-Old Children with Hearing Loss: A Community Study
Through a cross-sectional community study of 2044 children aged 2 years, we (1) examine the impact of hearing loss on early spoken expressive vocabulary outcomes and (2) investigate how early intervention-related factors impact expressive vocabulary ...
Peter Carew +8 more
doaj +1 more source
PSR J1740--3052: a pulsar with a massive companion [PDF]
We report on the discovery of a binary pulsar, PSR J1740-3052, during the Parkes multibeam survey. Timing observations of the 570-ms pulsar at Jodrell Bank and Parkes show that it is young, with a characteristic age of 350 kyr, and is in a 231-day, highly eccentric orbit with a companion whose mass exceeds 11 M_sun.
Stairs IH +16 more
+8 more sources
Modern zoos are increasingly taking a leading role in emergency management and wildlife recovery. In the face of climate change and the predicted increase in frequency and magnitude of catastrophic events, zoos provide specialised expertise to assist ...
Marissa L. Parrott +11 more
doaj +1 more source
Managing distress over time in psychotherapy : guiding the client in and through intense emotional work [PDF]
Clients who seek psychotherapeutic treatment have had personal experiences involving some form of distress. Although research has shown that the client's ability to experience and express painful emotions during therapy can have a therapeutic benefit, it
Muntigl, Peter
core +2 more sources
Gut microbiota composition during infancy and subsequent behavioural outcomes
Background: Despite intense interest in the relationship between gut microbiota and brain development, longitudinal data from human studies are lacking.
Amy Loughman +14 more
doaj +1 more source
There are mixed reports on the inclusion and use of 21 deoxycortisol (21DF) as the primary decision marker for classical 21-hydroxylase deficiency.
Ronda F. Greaves +7 more
doaj +1 more source
Lipid Metabolism Is Dysregulated in the Motor Cortex White Matter in Amyotrophic Lateral Sclerosis
Lipid metabolism is profoundly dysregulated in amyotrophic lateral sclerosis (ALS), yet the lipid composition of the white matter, where the myelinated axons of motor neurons are located, remains uncharacterised.
Gemma L. Sadler +8 more
doaj +1 more source
Convergence of matrices under random conjugation: wave packet scattering without kinematic entanglement [PDF]
In previous work, it was shown numerically that under successive scattering events, a collection of particles with Gaussian wavefunctions retains the Gaussian property, with the spread of the Gaussian ('Δx') tending to a value inversely proportional to ...
Schulman, Lawrence S. +1 more
core +1 more source

