Results 21 to 30 of about 29,588 (159)

A Spotlight on T Lymphocytes in Duchenne Muscular Dystrophy—Not Just a Muscle Defect

open access: yesBiomedicines, 2022
The lack of dystrophin in Duchenne muscular dystrophy (DMD) results in membrane fragility resulting in contraction-induced muscle damage and subsequent inflammation.
Chantal A. Coles   +3 more
doaj   +1 more source

Determinants of Clinical Decision Making under Uncertainty in Dentistry: A Scoping Review

open access: yesDiagnostics, 2023
Clinical decision-making for diagnosing and treating oral and dental diseases consolidates multiple sources of complex information, yet individual clinical judgements are often made intuitively on limited heuristics to simplify decision making, which may
Alexander Ivon King Murdoch   +10 more
doaj   +1 more source

Australia’s Role in Pneumococcal and Human Papillomavirus Vaccine Evaluation in Asia-Pacific

open access: yesVaccines, 2021
Australian researchers have made substantial contributions to the field of vaccinology over many decades. Two examples of this contribution relate to pneumococcal vaccines and the human papillomavirus (HPV) vaccine, with a focus on improving access to ...
Zheng Quan Toh   +5 more
doaj   +1 more source

Ex Vivo Restimulation of Human PBMC Expands a CD3+CD4-CD8-γδ+ T Cell Population That Can Confound the Evaluation of CD4 and CD8 T Cell Responses to Vaccination

open access: yesClinical and Developmental Immunology, 2013
The measurement of vaccine-induced humoral and CD4+ and CD8+ cellular immune responses represents an important correlate of vaccine efficacy. Accurate and reliable assays evaluating such responses are therefore critical during the clinical development ...
B. J. Sedgmen   +12 more
doaj   +1 more source

Ankle Dorsiflexor Function after Gastrocsoleus Lengthening in Children with Cerebral Palsy: A Literature Review

open access: yesMedicina, 2022
Background and Objectives: Ambulant children with cerebral palsy can demonstrate persistent “foot drop” after successful gastrocsoleus lengthening (GSL) surgery for equinus deformity.
Nicholas Sclavos   +5 more
doaj   +1 more source

Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3

open access: yesCell Reports, 2019
Summary: Necroptotic cell death has been implicated in many human pathologies and is thought to have evolved as an innate immunity mechanism. The pathway relies on two key effectors: the kinase receptor-interacting protein kinase 3 (RIPK3) and the ...
Emma J. Petrie   +18 more
doaj   +1 more source

The Young Binary Pulsar J1740–3052 [PDF]

open access: yesSymposium - International Astronomical Union, 2004
The young pulsar PSR J1740–3052, discovered in the Parkes Multibeam Pulsar Survey, is in a highly eccentric 8-month orbit with a companion of at least 11 solar masses. The up-to-date timing solution for this pulsar incorporates effects likely due to the spin mass quadrupole of the companion star; we discuss the implications for the geometry of the ...
openaire   +1 more source

Olfactory Bulb Volume Reflects Olfactory Dysfunction and Network Organization: Insights From the Population‐Based Rhineland Study

open access: yesInternational Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Olfactory dysfunction is common in aging and an early symptom of neurodegenerative diseases, but how structural (olfactory bulb [OB] volume) and functional (olfactory network [OFN] functional connectivity [FC]) brain features interact to shape odor identification ability remains unclear.
Weiyi Zeng   +4 more
wiley   +1 more source

Mental Health Impacts of the COVID-19 Pandemic on Australian Children and Adolescents with a Medical Condition: Longitudinal Findings

open access: yesCOVID
In Melbourne, Australia, strict ‘lockdowns’ were implemented in 2020 to suppress COVID-19, significantly disrupting daily life. Young people (
Louise M. Crowe   +18 more
doaj   +1 more source

Stem cell plasticity, acetylation of H3K14, and de novo gene activation rely on KAT7

open access: yesCell Reports, 2023
Summary: In the conventional model of transcriptional activation, transcription factors bind to response elements and recruit co-factors, including histone acetyltransferases.
Andrew J. Kueh   +16 more
doaj   +1 more source

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