Results 31 to 40 of about 30,542 (196)
Journal of Gynecologic Oncology, 2021 Objective To compare survival outcomes between bevacizumab (BEV) and olaparib (OLA) maintenance therapy in BRCA-mutated, platinum-sensitive relapsed (PSR) high-grade serous ovarian carcinoma (HGSOC).
S. I. Kim +11 more
semanticscholar +1 more source
Viral MLKL Homologs Subvert Necroptotic Cell Death by Sequestering Cellular RIPK3
Cell Reports, 2019 Summary: Necroptotic cell death has been implicated in many human pathologies and is thought to have evolved as an innate immunity mechanism. The pathway relies on two key effectors: the kinase receptor-interacting protein kinase 3 (RIPK3) and the ...
Emma J. Petrie +18 more
doaj +1 more source
The Young Binary Pulsar J1740–3052 [PDF]
Symposium - International Astronomical Union, 2004 The young pulsar PSR J1740–3052, discovered in the Parkes Multibeam Pulsar Survey, is in a highly eccentric 8-month orbit with a companion of at least 11 solar masses. The up-to-date timing solution for this pulsar incorporates effects likely due to the spin mass quadrupole of the companion star; we discuss the implications for the geometry of the ...
openaire +1 more source
Construction of a Feedback Comment Analysis Model for Evaluation of Endoscopic Surgical Skill
Annals of Gastroenterological Surgery, EarlyView.ABSTRACT Background Surgical education and skill assessments are important in improving surgical skills. However, instructors' comments tend to be complex and unorganized, with varying content and categories. This study aimed to develop a natural language processing (NLP) model to automatically classify feedback comments on surgical procedures and ...
Shusaku Iwai +7 more
wiley +1 more source
COVIDIn Melbourne, Australia, strict ‘lockdowns’ were implemented in 2020 to suppress COVID-19, significantly disrupting daily life. Young people (
Louise M. Crowe +18 more
doaj +1 more source
Vaccines, 2023 COVID-19 vaccine uptake among 5–11-year-olds is significantly lower than that of the 12+ age group. Some parents may have decided against vaccinating their children for COVID-19; others may be undecided and may be seeking more information to support ...
Zephaniah Hilton +3 more
doaj +1 more source
Thalidomide analogue CC-3052 reduces HIV+ neutrophil apoptosisin vitro [PDF]
Clinical and Experimental Immunology, 2000 SUMMARYThalidomide has significant immunomodulatory properties and has been used successfully in the treatment of oral ulcers and wasting in HIV patients. However, its use is limited by its poor bioavailability due to low solubility and short half life in solution, and teratogenic and neurotoxic side-effects.
M, Guckian +3 more
openaire +2 more sources
The Canadian Journal of Chemical Engineering, EarlyView.Supercritical water deasphalting. Abstract The removal of sulphur from heavy fuel oil (HFO) is essential to address environmental concerns and comply with the stringent regulations imposed by the International Maritime Organization (IMO) in 2020. Previously, the acceptable limit for sulphur was 3.5 wt.%, but it was recently changed to 0.5 wt.%.
Biswajit Saha +6 more
wiley +1 more source
Fragment screening for a protein-protein interaction inhibitor to WDR5
Structural Dynamics, 2019 The WD40-repeat protein WDR5 scaffolds various epigenetic writers and is a critical component of the mammalian SET/MLL histone methyltransferase complex.
Matthew L. Dennis +13 more
doaj +1 more source
Stem cell plasticity, acetylation of H3K14, and de novo gene activation rely on KAT7
Cell Reports, 2023 Summary: In the conventional model of transcriptional activation, transcription factors bind to response elements and recruit co-factors, including histone acetyltransferases.
Andrew J. Kueh +16 more
doaj +1 more source