Results 31 to 40 of about 29,588 (159)

Thalidomide analogue CC-3052 reduces HIV+ neutrophil apoptosisin vitro [PDF]

Clinical and Experimental Immunology, 2000
SUMMARYThalidomide has significant immunomodulatory properties and has been used successfully in the treatment of oral ulcers and wasting in HIV patients. However, its use is limited by its poor bioavailability due to low solubility and short half life in solution, and teratogenic and neurotoxic side-effects.
M, Guckian, I, Dransfield, P, Hay, A G, Dalgleish   +3 more
openaire   +2 more sources

Fast‐Track to Functional Neurons: Accessible and Minimalistic Neurogenin 2 Programming of Human iPSCs

Advanced NanoBiomed Research, EarlyView.
Fast‐track to functional human induced pluripotent stem cell (hiPSC)‐derived neurons: This colony‐initiated differentiation approach induces neurogenin 2 overexpression in dense hiPSC colonies (day 0), resulting in a structural reorganization of the colonies (day 2) before they are replated as single cells.
Jann Harberts, Malte Siegmund, Emma Wollesen, Caroline Viola, Kim Krieg, Ole Pless, Roey Elnathan, Robert Zierold, Robert H. Blick, Nicolas H. Voelcker   +9 more
wiley   +1 more source

Fragment screening for a protein-protein interaction inhibitor to WDR5

Structural Dynamics, 2019
The WD40-repeat protein WDR5 scaffolds various epigenetic writers and is a critical component of the mammalian SET/MLL histone methyltransferase complex.
Matthew L. Dennis, Benjamin J. Morrow, Olan Dolezal, Anthony N. Cuzzupe, Alexandra E. Stupple, Janet Newman, John Bentley, Meghan Hattarki, Stewart D. Nuttall, Richard C. Foitzik, Ian P. Street, Paul A. Stupple, Brendon J. Monahan, Thomas. S. Peat   +13 more
doaj   +1 more source

An Endophytic Diaporthe apiculatum Produces Monoterpenes with Inhibitory Activity against Phytopathogenic Fungi

Antibiotics, 2019
Volatile organic compounds (VOCs) from endophytic fungi are becoming a potential antibiotic resource. The inhibitive effects of VOCs produced by an endophytic fungus in Leucaena leucocephala were investigated on plant pathogens in this study.
Xiao-Yu Song, Huihua Wang, Fei Ren, Kaiying Wang, Guiming Dou, Xing Lv, Dong-Hui Yan, Gary Strobel   +7 more
doaj   +1 more source

Reducing COVID-19 Vaccine Decisional Conflict in Parents of 5–11-Year-Old Children in Australia: A Single Arm Pre-Post Study

Vaccines, 2023
COVID-19 vaccine uptake among 5–11-year-olds is significantly lower than that of the 12+ age group. Some parents may have decided against vaccinating their children for COVID-19; others may be undecided and may be seeking more information to support ...
Zephaniah Hilton, Monsurul Hoq, Margie Danchin, Jessica Kaufman   +3 more
doaj   +1 more source

Green Synthesis and Application of New Antioxidant 3052

IOP Conference Series: Materials Science and Engineering, 2020
Abstract A new synthetic antioxidant, 4-methyl-2-tert-butyl-6-(4-methyl-3-tert-butyl-2-hydroxybenzyl)phenyl acrylate (3052) was developed. Using solid phosgene as green acyl chloride reagent, DMF as initiator, acrylic acid and 2246 bisphenol as raw materials, two-component synthesis of antioxidant 4-methyl-2-tert-butyl-6-(4-methyl-3-tert-
Jun-Lin Guo, Xi-Wang Tong, Ming Xin, Li-Ying Yu, Bo Ning   +4 more
openaire   +1 more source

Spatially resolved 23Na magnetic resonance dispersion measurement in porous media

The Canadian Journal of Chemical Engineering, EarlyView.
Quantitative 23Na MRI was employed to analyze dispersion in realistic core plug samples and was compared with the conventional breakthrough curve. 23Na MRI provided a more effective aassessment of core plug heterogeneity than the conventional method. Abstract Tracer tests are widely used in the petroleum industry to assess reservoir core plugs, relying
Rheya Rajeev, Mohammad Sadegh Zamiri, Andrés Ramírez Aguilera, Florea Marica, Laura Romero de Zerón, Bruce J. Balcom   +5 more
wiley   +1 more source

Toxicity and Availability of Manganese in the Growth of Tropical Grasses in Contaminated Soil

Applied and Environmental Soil Science
Phytoremediation is a technique with high viability due to its low cost and minimal environmental impact. However, there are a few results regarding the use of tropical grasses in the phytoremediation of manganese (Mn), and there is no clear definition ...
Enilson de Barros Silva, Willian Cleisson Lopes de Souza, Barbara Olinda Nardis, Luís Reynaldo Ferracciú Alleoni, Paulo Henrique Grazziotti, Lauana Lopes dos Santos, Iracema Raquel Santos Bezerra, Flávio Antônio Fernandes Alves, Wesley Costa Silva, Bento Gil Uane, Sandra Antunes do Nascimento   +10 more
doaj   +1 more source

SARS-CoV-2 Multi-Antigen Serology Assay

Methods and Protocols, 2021
Serology tests are extremely useful for assessing whether a person has been infected with a pathogen. Since the onset of the COVID-19 pandemic, measurement of anti-SARS-CoV-2-specific antibodies has been considered an essential tool in identifying ...
Ramin Mazhari, Shazia Ruybal-Pesántez, Fiona Angrisano, Nicholas Kiernan-Walker, Stephanie Hyslop, Rhea J. Longley, Caitlin Bourke, Catherine Chen, Deborah A. Williamson, Leanne J. Robinson, Ivo Mueller, Emily M. Eriksson   +11 more
doaj   +1 more source

Prevalence and local factors associated with radiographic bone loss in primary dentition: A retrospective study

Journal of Periodontology, EarlyView.
Abstract Background This study aimed to evaluate the radiographic bone level in primary molars in a Brazilian population, define the prevalence of bone loss, and identify the local factors associated with early bone alterations. Methods Radiographs of children who attended Piracicaba Dental School (Brazil) between 2014 and 2020 were evaluated.
Murilo C. Paraluppi, Camila S. Stolf, Bianca Mendes, Marcio Z. Casati, Karina G. Silvério, Enilson A. Sallum, Renato C. V. Casarin, Mabelle F. Monteiro   +7 more
wiley   +1 more source