Results 121 to 130 of about 300,550 (327)

A Cre‐dependent lentiviral vector for neuron subtype‐specific expression of large proteins

FEBS Letters, EarlyView.
We designed a versatile and modular lentivector comprising a Cre‐dependent switch and self‐cleaving 2A peptide and tested it for co‐expression of GFP and a 2.8 kb gene of interest (GOI) in mouse cortical parvalbumin (PV+) interneurons and midbrain dopamine (TH+) neurons.
Weixuan Xue, Sandrine Picaud, Régine Hepp, Stéphanie Pons, Uwe Maskos, Bertrand Lambolez, Ludovic Tricoire   +6 more
wiley   +1 more source

Limiting 20S proteasome assembly leads to unbalanced nucleo-cytoplasmic distribution of 26S/30S proteasomes and chronic proteotoxicity

iScience
Summary: In addition to the degradation of cell-cycle proteins, short-lived, damaged, or unfolded proteins are constantly cleared from cells by the proteasome.
Gabriel Ruiz-Romero, María Dolores Berdún, Mark Hochstrasser, Silvia Salas-Pino, Rafael R. Daga   +4 more
doaj   +1 more source

Tool life of diamond inserts after laser assisted turning of cemented carbides

MATEC Web of Conferences, 2017
The paper presents results and discussion on parameters influence on tool life when turning laser cladded cemented carbides under laser assisted machining (LAM) conditions. The layers are known as Technolase 30S.
Kieruj Piotr, Kuklinski Mateusz
doaj   +1 more source

Efficient reconstitution of functional Escherichia coli 30S ribosomal subunits from a complete set of recombinant small subunit ribosomal proteins [PDF]

, 1999
Gloria M. Culver, Harry F. Noller
openalex   +1 more source

Increased insolation threshold for runaway greenhouse processes on Earth like planets

, 2013
Because the solar luminosity increases over geological timescales, Earth climate is expected to warm, increasing water evaporation which, in turn, enhances the atmospheric greenhouse effect.
A Arking, A Borysow, A Bucholtz, Alizée Pottier, AP Ingersoll, B Charnay, B Van Leer, Benjamin Charnay, BJ Soden, C Goldblatt, C Goldblatt, C Richard, DMW Frierson, DO Gough, E Wolf, F Forget, F Forget, F Hourdin, F Selsis, Francois Forget, G Le Hir, GC Simpson, GL Mellor, H Le Treut, J Leconte, J Yang, JE Hansen, JF Kasting, JF Kasting, JF Kasting, Jérémy Leconte, LS Rothman, M Ishiwatari, M Komabayashi, O Boucher, OB Toon, R Wordsworth, R Wordsworth, RD Wordsworth, RK Kopparapu, Robin Wordsworth, RT Pierrehumbert, RT Pierrehumbert, RT Pierrehumbert, S Clough, S Manabe, S Nakajima, SC Sherwood, V Ramanathan, Y Abe   +49 more
core   +4 more sources

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Creation of a scientific agrarian discourse at the end of the 20s - in the 30s. XX century in the Ukrainian SSR [PDF]

, 2020
N. Shchebetyuk
openalex   +1 more source

Hematopoietic (stem) cells—The elixir of life?

FEBS Letters, EarlyView.
The aging of HSCs (hematopoietic stem cells) and the blood system leads to the decline of other organs. Rejuvenating aged HSCs improves the function of the blood system, slowing the aging of the heart, kidney, brain, and liver, and the occurrence of age‐related diseases.
Emilie L. Cerezo, Jonah Anderson, Emilie Dinh Vedrenne, Noël Yeh Martín, Jette Lengefeld   +4 more
wiley   +1 more source

Perception on Abortion among Korean Men in their 20s and 30s [PDF]

, 2017
Geum-Nam Kim, Kye Ha Kim
openalex   +1 more source

Retirement Security Across Generations: Are Americans Prepared for Their Golden Years? [PDF]

, 2013
When the Great Recession hit in 2007, the oldest baby boomers were nearly eligible for Social Security. Many of them recalled stories of the Great Depression and feared that their own nest eggs would vanish with too little time to make up the losses ...

core