Results 161 to 170 of about 297,139 (334)
Mechanisms and kinetic assays of aminoacyl‐tRNA synthetases
FEBS Letters, EarlyView.
Igor Zivkovic+2 more
wiley +1 more source
TOMM20 increases cancer aggressiveness by maintaining a reduced state with increased NADH and NADPH levels, oxidative phosphorylation (OXPHOS), and apoptosis resistance while reducing reactive oxygen species (ROS) levels. Conversely, CRISPR‐Cas9 knockdown of TOMM20 alters these cancer‐aggressive traits.
Ranakul Islam+9 more
wiley +1 more source
Explosive hydrogen burning during type I X-ray bursts [PDF]
Explosive hydrogen burning in type I X-ray bursts (XRBs) comprise charged particle reactions creating isotopes with masses up to A~100. Since charged particle reactions in a stellar environment are very temperature sensitive, we use a realistic time ...
Fisker, Jacob Lund+2 more
core +2 more sources
The Snowdonia National Park, by W. M. Condry. Collins, New Naturalist, 30s. [PDF]
Colin Matheson
openalex +1 more source
Presurgery 72‐h fasting in GB patients leads to adaptations of plasma lipids and polar metabolites. Fasting reduces lysophosphatidylcholines and increases free fatty acids, shifts triglycerides toward long‐chain TGs and increases branched‐chain amino acids, alpha aminobutyric acid, and uric acid.
Iris Divé+7 more
wiley +1 more source
Transcriptome‐wide analysis of circRNA and RBP profiles and their molecular relevance for GBM
CircRNAs are differentially expressed in glioblastoma primary tumors and might serve as therapeutic targets and diagnostic markers. The investigation of circRNA and RNA‐binding proteins (RBPs) interactions shows that distinct RBPs play a role in circRNA biogenesis and function.
Julia Latowska‐Łysiak+14 more
wiley +1 more source
L. E. Elsgolc, Calculus of Variations (International series of monographs on Pure and Applied Mathematics, Vol. 19, Pergamon Press, Oxford, 1961), 178 pp., 30s. [PDF]
R. P. Gillespie
openalex +1 more source
This study investigates an alternative approach to reactivating the oncosuppressor p53 in cancer. A short peptide targeting the association of the two p53 inhibitors, MDM2 and MDM4, induces an otherwise therapeutically active p53 with unique features that promote cell death and potentially reduce toxicity towards proliferating nontumor cells.
Sonia Valentini+10 more
wiley +1 more source
Impacts of horizontal resolution on simulated climate statistics in ECHAM4
The sensitivity of a general circulation model to changes in resolution is studied using the Max Planck Institute for Meteorology (MPI) 19-level model, ECHAM4.
Roeckner, E., Stendel, M.
core