Results 191 to 200 of about 297,139 (334)

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

Molecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu, Dilara Demirci, Sude Eris, Bengisu Dayanc, Ece Cakiroglu, Merve Basol, Merve Uysal, Gulcin Cakan‐Akdogan, Fang Liu, Mehmet Ozturk, Gökhan Karakülah, Serif Senturk   +11 more
wiley   +1 more source

Birds and Wild Africa, by William Condry. Collins, 30s. [PDF]

, 1968
C. W. Benson
openalex   +1 more source

Limiting 20S proteasome assembly leads to unbalanced nucleo-cytoplasmic distribution of 26S/30S proteasomes and chronic proteotoxicity

iScience
Summary: In addition to the degradation of cell-cycle proteins, short-lived, damaged, or unfolded proteins are constantly cleared from cells by the proteasome.
Gabriel Ruiz-Romero, María Dolores Berdún, Mark Hochstrasser, Silvia Salas-Pino, Rafael R. Daga   +4 more
doaj  

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

Molecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau, Hayley S. Smith, Begüm Alural, Claire E. Martin, Laura A. New, Manali Tilak, Sara L. Banerjee, Hannah N. Robeson, Nicolas Bisson, Anne‐Claude Gingras, Jasmin Lalonde, Nina Jones   +11 more
wiley   +1 more source

LOCALIZATION OF KANAMYGIN SENSITIVITY IN THE 23S CORE OF 30S RIBOSOMES OF E. COLI

, 1968
Hiroshi Masukawa, Nobuo Tanaka, HAMAO UMEZAWA   +2 more
openalex   +2 more sources

Waclaw Sierpiński A Selection of Problems in the Theory of Numbers, translated from the Polish by A. Sharma (Popular Lectures in Mathematics, Vol. 11, Pergamon Press, 1964), 126 pp., 30s. [PDF]

, 1966
R. A. Rankin
openalex   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

Molecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit, Thais Pereira‐Veiga, Helena Brauer, Michael Horn, Paula Nissen, Thomas Mair, Bente Siebels, Hannah Voß, Ruimeng Zhuang, Marie‐Therese Haider, Desiree Loreth, Margarita Iskhakova, Bele Lindemann, Julian Kött, Laure Cayrefourcq, Jasmin Wellbrock, Hartmut Schlüter, Klaus Pantel, Catherine Alix‐Panabières, Manfred Jücker   +19 more
wiley   +1 more source

Estimating undiagnosed HIV infections by age group in Japan: an extended age-dependent back-calculation. [PDF]

Infect Dis Model
Fujiwara S, Nishiura H, Shirasaka T, Imamura A.   +3 more
europepmc   +1 more source

Clinical Practice and Physiology of Artificial Respiration. By Spalding J. M. K. and Crampton-Smith A. Published by Blackwell Scientific Publications, Ltd., Oxford. Pp. 140; illustrated Price 30s.

, 1963
J. M. K. Spalding
openalex   +1 more source

Vanishing Wild Animals of the World by Richard Fitter. Midland Bank and Kaye & Ward, 30s. - Extinct and Vanishing Animals by Vincenz Ziswiler. Longmans & Springer, 35s. [PDF]

, 1968
Ivor Montagu
openalex   +1 more source