Results 241 to 250 of about 297,139 (334)

Distant ribose 2'-O-methylation of 23S rRNA helix 69 pre-orders the capreomycin drug binding pocket at the ribosome subunit interface. [PDF]

Nucleic Acids Res
Nandi S, Dey D, Srinivas P, Dunham CM, Conn GL.   +4 more
europepmc   +1 more source

In vivo X-ray footprinting of pre-30S ribosomes reveals chaperone-dependent remodeling of late assembly intermediates.

Molecules and Cells, 2013
Sarah F. Clatterbuck Soper, Romel P Dator, P. Limbach, S. Woodson   +3 more
semanticscholar   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

Molecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine, Sterenn Guillemot, Louis‐Bastien Weiswald, Romane Florent, Edwige Abeilard, Florence Giffard, Emilie Brotin, Mélanie Briand, Enora Dolivet, Laurent Poulain, Marie Villedieu   +10 more
wiley   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

Molecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte, Osheen Sharma, Laura Leuenberger, Emelie Wallin, Josefin Fernebro, Päivi Östling, Rebecka Bergström, Johan Lindberg, Ulrika Joneborg, Olli Kallioniemi, Brinton Seashore‐Ludlow   +10 more
wiley   +1 more source

A Study of Differences in Enjoyment, Exercise Commitment, and Intention to Continue Participation Among Age Groups of Adult Amateur Golfers. [PDF]

Behav Sci (Basel)
Yang HJ, Yang JH, Choi C, Bum CH.
europepmc   +1 more source

Effect of Initiation Factor 3 Binding on the 30S Ribosomal Subunits of Escherichia coli [PDF]

, 1974
Cynthia L. Pon, Claudio O. Gualerzi
openalex   +1 more source

Rotation of the head of the 30S ribosomal subunit during mRNA translocation

Proceedings of the National Academy of Sciences of the United States of America, 2012
Zhuojun Guo, H. Noller
semanticscholar   +1 more source

Comprehensive omics‐based classification system in adult patients with B‐cell acute lymphoblastic leukemia

Molecular Oncology, EarlyView.
The COMBAT classification system, developed through multi‐omics integration, stratifies adult patients with B‐cell acute lymphoblastic leukemia(B‐ALL) into three molecular subtypes with distinct surface antigen patterns, immune landscape, methylation patterns, biological pathways and prognosis.
Yang Song, Ting Liu, Qishan Hao, Qiuyun Fang, Xiaoyuan Gong, Yan Li, Zheng Tian, Hui Wei, Min Wang, Jianxiang Wang, Tao Cheng, Yingchang Mi   +11 more
wiley   +1 more source

A noteworthy issue: microbiome data variation depending on sampling methods in skin microecology studies in acne vulgaris patients. [PDF]

Front Immunol
Xu DT, Chen Q, Yang JY, Yan GR, Zhang LL, Liu XJ, Wang PR, Liu J, Wang XL.   +8 more
europepmc   +1 more source

Ethical Responsibility in Medicine. A Christian Approach. Edited by Vincent Edmunds, M.D., M.R.C.P., and C. Gordon Scorer, M.D., F.R.C.S., with twelve other contributors. 9 x 5¾ in. Pp. viii + 200. Index. 1967. Edinburgh and London: E. & S. Livingstone Ltd. Price 30s

, 1967
H. J. Seddon
openalex   +1 more source