Results 261 to 270 of about 297,139 (334)

Novel archaeal ribosome dimerization factor facilitating unique 30S-30S dimerization. [PDF]

Nucleic Acids Res
Hassan AH, Pinkas M, Yaeshima C, Ishino S, Uchiumi T, Ito K, Demo G.   +6 more
europepmc   +1 more source

Interaction of Escherichia coli 30S Ribosomal Subunits with MS2 Phage RNA in the Absence of Initiation Factors

, 1974
W. Szer, Steven Leffler
openalex   +1 more source

Genomics‐led approach to drug testing in models of undifferentiated pleomorphic sarcoma

Molecular Oncology, EarlyView.
GA text Genomic data from undifferentiated pleomorphic sarcoma patients and preclinical models were used to inform a targeted drug screen. Selected compounds were tested in 2D and 3D cultures of UPS cell lines. A combination of trametinib and infigratinib was synergistic in the majority of UPS cell lines tested, which was further confirmed in an ex ...
Piotr J. Manasterski, Molly R. Danks, John P. Thomson, Morwenna Muir, Martin Lee, John C. Dawson, Ana T. Amaral, Juan Diaz‐Martin, David S. Moura, Javier Martin‐Broto, Ali Alsaadi, Donald M. Salter, Ailsa J. Oswald, Graeme Grimes, Larry Hayward, Ted R. Hupp, Karen Sisley, Paul H. Huang, Neil O. Carragher, Valerie G. Brunton   +19 more
wiley   +1 more source

Evaluation the static precise point positioning and fixing rate with phase ambiguity resolution using different analysis centers products. [PDF]

PLoS One
Sun X, Yao J, Yang Z.
europepmc   +1 more source

RsgA releases RbfA from 30S ribosome during a late stage of ribosome biosynthesis

EMBO Journal, 2011
S. Goto, Shingo Kato, Takatsugu Kimura, A. Muto, H. Himeno   +4 more
semanticscholar   +1 more source

A nucleotide‐independent, pan‐RAS‐targeted DARPin elicits anti‐tumor activity in a multimodal manner

Molecular Oncology, EarlyView.
We report a Designed Ankyrin Repeat Protein that binds and inhibits RAS proteins, which serve as central cell signaling hubs and are essential for the progression of many cancers. Its unique feature is that it does not discriminate between different RAS isoforms or mutations and is capable of binding to RAS in both its active (GTP‐bound) and inactive ...
Jonas N. Kapp, Wouter P. R. Verdurmen, Jonas V. Schaefer, Kari Kopra, Gabriela Nagy‐Davidescu, Elodie Richard, Marie‐Julie Nokin, Patrick Ernst, Rastislav Tamaskovic, Martin Schwill, Ralph Degen, Claudia Scholl, David Santamaria, Andreas Plückthun   +13 more
wiley   +1 more source

Halloysite-Nanotube-Mediated High-Flux γ-Al₂O₃ Ultrafiltration Membranes for Semiconductor Wastewater Treatment. [PDF]

Membranes (Basel)
Geng S, Chen D, Guo Z, Li Q, Wen M, Wang J, Guo K, Wang J, Wang Y, Yu L, Li X, Li X.   +11 more
europepmc   +1 more source

Structural basis for the function of a small GTPase RsgA on the 30S ribosomal subunit maturation revealed by cryoelectron microscopy

Proceedings of the National Academy of Sciences of the United States of America, 2011
Q. Guo, Yi Yuan, Yanji Xu, B. Feng, Liang Liu, Kai Chen, Ming Sun, Zhixiu Yang, Jianlin Lei, N. Gao   +9 more
semanticscholar   +1 more source

Therapeutic applications of a novel humanized monoclonal antibody targeting chemokine receptor CCR9 in pancreatic cancer

Molecular Oncology, EarlyView.
C–C chemokine receptor type 9 (CCR9) is an immune checkpoint in pancreatic ductal adenocarcinoma (PDAC). Novel anti‐CCR9 antibody SRB2 was evaluated in combination with cytotoxic chemotherapy in PDAC cells, patient‐derived organoids, patient‐derived xenografts, and humanized mouse models.
Hannah G. McDonald, Anna M. Reagan, Charles J. Bailey, Mei Gao, Muqiang Gao, Angelica L. Solomon, Michael J. Cavnar, Prakash K. Pandalai, Mautin T. Barry‐Hundeyin, Megan M. Harper, Justin A. Rueckert, Ángela Turrero, Araceli Tobio, Anxo Vidal, Daniel Roca‐Lema, Elia Álvarez‐Coiradas, Pablo Garrido, Laureano Simón, Joseph Kim   +18 more
wiley   +1 more source

Defining the networks that connect RNase III and RNase J-mediated regulation of primary and specialized metabolism in <i>Streptomyces venezuelae</i>. [PDF]

J Bacteriol
Pepler MAD, Mulholland EL, Montague FR, Elliot MA.   +3 more
europepmc   +1 more source