Results 101 to 110 of about 2,472,075 (322)

Thyroid Hormone Receptor β1 and PGC1α Coordinately Regulate OPA1/MFN2‐Mediated Mitochondrial Fusion and UCP1‐Mediated Lipid Browning in ccRCC

open access: yesAdvanced Science, EarlyView.
Thyroid hormone receptor β1 (TRβ) downregulation correlates with poor prognosis in clear cell renal cell carcinoma (ccRCC). Restoration of TRβ and the peroxisome proliferator‐activated receptor gamma coactivator 1‐alpha suppresses tumor progression in ccRCC through Uncoupling protein 1 mediated tumor cell “slimming” and optic atrophy 1/mitofusin 2 ...
Xiangui Meng   +6 more
wiley   +1 more source

Review: Aspinall, Edward and Marcus Mietzner (eds.) (2010), Problems of Democratisation in Indonesia: Elections, Institutions and Society

open access: yesJournal of Current Southeast Asian Affairs, 2010
Review of the edited volume:Aspinall, Edward and Marcus Mietzner (eds.) (2010), Problems of Democratisation in Indonesia: Elections, Institutions and Society, Singapore: Institute of Southeast Asian StudiesISBN: 978-981-4279-90-1, 359 ...
Vera Altmeyer
doaj  

Polysaccharide Adjuvants as Innate Immune Trainers: Bridging Pattern Recognition Receptor (PRR) Activation and Metabolic Reprogramming for Synthetic Vaccine Design

open access: yesAdvanced Science, EarlyView.
Polysaccharides modulate immune responses by engaging pattern recognition receptors (PRRs) to induce T‐cell activation. In vaccine design, their particle size critically influences lymph node targeting and activation mechanisms. By engineering structural complexity and multivalent PRR engagement, polysaccharides enable precise modulation of immune ...
Jeong Hyun Moon   +8 more
wiley   +1 more source

Review: Somchai Phatharathananunth (2006), Civil Society and Democratization. Social Movements in Northeast Thailand Buchbesprechung: Somchai Phatharathananunth (2006), Civil Society and Democratization. Social Movements in Northeast Thailand

open access: yesJournal of Current Southeast Asian Affairs, 2009
Book Review of Somchai Phatharathananunth (2006), Civil Society and Democratization. Social Movements in Northeast Thailand, Copenhagen: NIAS Press; ISBN 10: 8791114381, 251 pages.
Wolfram Schaffar
doaj  

Single‐Cell Dissection Reveals Immune Dysregulation After CD5 or CD7‐Directed Chimeric Antigen Receptor T‐Cell Therapy

open access: yesAdvanced Science, EarlyView.
Single‐cell RNA/TCR/BCR sequencing reveals that 5CAR therapy in T‐ALL induces T‐cell exhaustion, reduces EBV‐associated TCRs, lowers TCR/BCR diversity, and increases NK/DC/monocyte activation and function. In contrast, 7CAR therapy reduces multiple pathogen‐associated TCRs, enhances NK cell activation and function, decreases monocyte activation, and ...
Yuechen Luo   +12 more
wiley   +1 more source

Micro-social and Contextual Sources of Democratic Attitudes in Latin America Las fuentes microsociales y contextuales de las actitudes democráticas en América Latina

open access: yesJournal of Politics in Latin America, 2011
Many Latin American countries democratized between 1975 and 2000, and research has confirmed that contemporary Latin Americans hold democratic political attitudes.
Eduardo Salinas, John A. Booth
doaj  

Multiscale Design of Dental Restorative Materials: Mechanistic Foundations, Technological Innovations, and Clinical Translation

open access: yesAdvanced Science, EarlyView.
From conventional ceramics to bioinspired smart composites, this review charts the evolution of dental restorative biomaterials. Integrating materials innovation, advanced manufacturing technologies, and bioinspired strategies, it presents a roadmap for developing functional, clinically translatable restorations that combine durability, adaptability ...
Bailei Li   +14 more
wiley   +1 more source

Introduction: The Massacres of 1965–1966: New Interpretations and the Current Debate in Indonesia

open access: yesJournal of Current Southeast Asian Affairs, 2013
The mass violence which spread across Indonesia following an attempt-ed coup on 1 October 1965 claimed the lives of half a million people and irrevocably changed the lives of millions more.
Annie Pohlman
doaj  

Environmental and Ecological Monitoring with Biodegradable Technologies

open access: yesAdvanced Science, EarlyView.
This review examines the development and application of wireless biodegradable sensors for environmental monitoring. It explores (bio)degradable materials, their degradation mechanisms in various environments, and non‐toxic fabrication techniques. Additionally, it addresses scalable production and sustainable powering solutions, emphasizing the high ...
Mohammad Javad Bathaei   +7 more
wiley   +1 more source

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