Results 71 to 80 of about 256,941 (291)

Light Activation of the Phosphoinositide Cycle in Intrinsically Photosensitive Chicken Retinal Ganglion Cells [PDF]

open access: yes, 2010
Purpose: In vertebrates, intrinsically photosensitive retinal ganglion cells (ipRGCs) acting as nonvisual photoreceptors transmit environmental illumination information to the brain, regulating diverse non–image-forming tasks.
Contin, Maria Ana   +5 more
core   +1 more source

Plastid Engineering for Photosynthesis‐Driven Synthesis of Hyaluronic Acid in Tobacco

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Hyaluronic acid (HA) is a glycosaminoglycan composed of alternating units of N‐acetylglucosamine and glucuronic acid. High moisture retention, viscoelasticity and biocompatibility are unique features that make HA polymers attractive compounds for medical applications and aesthetic purposes.
Amanda Lopes   +10 more
wiley   +1 more source

SLC19A1 transports immunoreactive cyclic dinucleotides. [PDF]

open access: yes, 2019
The accumulation of DNA in the cytosol serves as a key immunostimulatory signal associated with infections, cancer and genomic damage1,2. Cytosolic DNA triggers immune responses by activating the cyclic GMP-AMP synthase (cGAS)-stimulator of interferon ...
Corn, Jacob E   +10 more
core  

Expression of a Bacterial Trehalose 6‐Phosphate Synthase Gene otsA in Camelina sativa Seeds Promotes the Channelling of Carbon Towards Oil Accumulation

open access: yesPlant Biotechnology Journal, EarlyView.
ABSTRACT Improving seed oil yield is essential for developing Camelina sativa as a sustainable biofuel crop. Fatty acid synthesis depends on the production of acetyl‐CoA from photosynthetically derived sugars. Trehalose 6‐phosphate (T6P), a proxy for sucrose availability, can link sugar status to plant growth and development. Synthesised by trehalose 6‐
Saroj Kumar Sah   +7 more
wiley   +1 more source

Semi-Automated PCR Method for Quantitating MDR1 Expression

open access: yesBioTechniques, 1996
The MDR1 gene is involved in drug resistance in many hematopoietic and solid tumors. The Quantitative PCR System 5000TM (QPCR-5000; Perkin-Elmer) is a new instrument system that uses electrochemiluminescence to automatically quantitate polymerase chain ...
S. Zhao   +5 more
doaj   +1 more source

APE1 Activity is Controlled by Non‐G‐Quadruplex Conformations in Single‐ and Double‐Stranded G‐Quadruplex Constructs

open access: yesChemistry – A European Journal, Volume 32, Issue 5, 2 February 2026.
G‐quadruplex (G4) folding in DNA is inhibitory to AP endonuclease, although the protein still binds well to G4s. Curiously, partially folded G‐rich sequences, possibly transient hairpins, containing AP are very good substrates for cleavage by APE1. Herein, the enzyme activity and G4 folding are studied in single‐stranded vs. duplex contexts.
Brianna L. Trabucco   +2 more
wiley   +1 more source

Alternatives to NIST Cf-252 Iirradiations for Transfer Calibration of S-32 Neutron Monitors [PDF]

open access: yesEPJ Web of Conferences
Gas-flow proportional counting systems are used by the Radiation Metrology Laboratory (RML) at Sandia National Laboratories for reactor fluence monitoring with the 32S(n,p)32P reaction.
Vehar David   +2 more
doaj   +1 more source

Differences in Src phosphorylation of PSD‐93 and PSD‐95 drive differences in scaffolding activity

open access: yesProtein Science, Volume 35, Issue 2, February 2026.
Abstract Scaffold proteins contain multiple binding modules that allow for co‐localization of proteins that lack a direct interaction. Evolution resulted in different combinations of binding modules that rewired existing signal transduction pathways.
Frank A. Mindlin   +3 more
wiley   +1 more source

Stimulation by serum of 32P incorporation into the phospholipids of Ehrlich ascites cells

open access: yesJournal of Lipid Research, 1977
Ehrlich ascites cells adapted for suspension culture were incubated with 32PO43- in a Krebs-Ringer-HEPES (N-2-hydroxyethyl-piperazine-N'-2-ethanesulfonate) buffer with or without 5% calf serum.
P B Schneider
doaj   +1 more source

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