Results 11 to 20 of about 2,185,143 (332)

Exosomal microRNA-342-5p secreted from adipose-derived mesenchymal stem cells mitigates acute kidney injury in sepsis mice by inhibiting TLR9

Biological Procedures Online, 2023
Background Sepsis-related acute kidney injury (AKI) is an inflammatory disease associated with extremely high mortality and health burden. This study explored the possibility of exosomes secreted by adipose-derived mesenchymal stem cells (AMSCs) serving ...
Wei Liu, Chenghuan Hu, Buyao Zhang, Mingxia Li, Fuxing Deng, Shuangping Zhao   +5 more
doaj   +2 more sources

Human Umbilical Cord Mesenchymal Stem Cells Inhibit Pyroptosis of Renal Tubular Epithelial Cells through miR-342-3p/Caspase1 Signaling Pathway in Diabetic Nephropathy

Stem Cells International, 2023
Diabetic nephropathy (DN) is one of the microvascular complications of diabetes. Recent studies suggest that the pyroptosis of renal tubular epithelial cell plays a critical role in DN.
Shuo Zheng, Ke Zhang, Yaqi Zhang, Jing He, Ouyang Yu, Ruibo Lang, Chunchun Ao, Yijia Jiang, Huan Xiao, Yu Li, Mao Li, Changyong Li, Dongcheng Wu   +12 more
semanticscholar   +1 more source

The N6-methyladenosine modification of circALG1 promotes the metastasis of colorectal cancer mediated by the miR-342-5p/PGF signalling pathway

Molecular Cancer, 2022
Background Previous studies have shown that the N 6 -methyladenosine (m 6 A) modification enhances the binding ability of mRNAs/long noncoding RNAs (lncRNAs) to microRNAs (miRNAs), but the impact of this modification on the competitive endogenous RNA ...
Changwei Lin, M. Ma, Yi Zhang, Liang Li, Fei Long, Canbin Xie, Hua Xiao, Teng Liu, Buning Tian, Kaiyan Yang, Yihang Guo, Miao Chen, Jinjiang Chou, N. Gong, Xiaorong Li, G. Hu   +15 more
semanticscholar   +1 more source

Exosomal LncRNA LINC00659 transferred from cancer-associated fibroblasts promotes colorectal cancer cell progression via miR-342-3p/ANXA2 axis

Journal of Translational Medicine, 2021
Background Cancer-associated fibroblasts (CAFs) play a pivotal role in regulating tumor progression by transferring exosomes to adjacent cells. Our aim was to clarify the role of LINC00659 encapsulated in CAFs-derived exosomes (CAFs-exo) in colorectal ...
Lin Zhou, Jian Li, Yaping Tang, Mei Yang
semanticscholar   +1 more source

LncRNA TP73‐AS1 promotes nasopharyngeal carcinoma progression through targeting miR-342-3p and M2 polarization via exosomes

Cancer Cell International, 2022
Background Nasopharyngeal carcinoma (NPC) is a deadly cancer, mainly presenting in southeast and east Asia. Long noncoding RNAs (lncRNAs) play essential roles in cancer progression. Exosomes are critical for intercellular communication.
Hongchao Yao, L. Tian, B. Yan, Like Yang, Yushan Li   +4 more
semanticscholar   +1 more source

Macrophage-derived exosomal miR-342-3p promotes the progression of renal cell carcinoma through the NEDD4L/CEP55 axis

Oncology Research, 2022
Due to its difficulty in early diagnosis and lack of sensitivity to chemotherapy and radiotherapy, renal cell carcinoma (RCC) remains to be a frequent cause of cancer-related death.
J. Feng, Beiping Xu, Chunmei Dai, Yaodong Wang, G. Xie, Wenyu Yang, Bingshu Zhang, Xiao-han Li, Jun Wang   +8 more
semanticscholar   +1 more source

Circulating Small Extracellular Vesicle-Derived miR-342-5p Ameliorates Beta-Amyloid Formation via Targeting Beta-site APP Cleaving Enzyme 1 in Alzheimer’s Disease

Cells, 2022
Alzheimer’s disease (AD) is a common neurodegenerative disorder with progressive cognitive impairment in the elderly. Beta-amyloid (Aβ) formation and its accumulation in the brain constitute one of the pathological hallmarks of AD.
Zhiwu Dong, Hongjun Gu, Qiang Guo, Xianglu Liu, Feifei Li, Huiling Liu, Li Sun, Huimin Ma, Kewen Zhao   +8 more
semanticscholar   +1 more source

CircRNF144B/miR-342-3p/FBXL11 axis reduced autophagy and promoted the progression of ovarian cancer by increasing the ubiquitination of Beclin-1

Cell Death and Disease, 2022
Circular RNAs (circRNAs) can regulate autophagy and ovarian cancer (OC) progression. However, autophagy-associated circRNAs involved in OC progression are largely unknown.
Wenting Song, Zhirui Zeng, Yilei Zhang, Haili Li, Huimin Cheng, Jun Wang, Fengrui Wu   +6 more
semanticscholar   +1 more source

TNF-alpha-induced microglia activation requires miR-342: impact on NF-kB signaling and neurotoxicity

Cell Death and Disease, 2020
Growing evidences suggest that sustained neuroinflammation, caused by microglia overactivation, is implicated in the development and aggravation of several neurological and psychiatric disorders.
J. P. Brás, Joana Bravo, Jaime Freitas, M. Barbosa, S. Santos, T. Summavielle, M. Almeida   +6 more
semanticscholar   +1 more source

Extracellular Vesicle-Derived circITGB1 Regulates Dendritic Cell Maturation and Cardiac Inflammation via miR-342-3p/NFAM1

Oxidative Medicine and Cellular Longevity, 2022
Acute myocardial infarction (AMI) is a complication of atherosclerosis‐related cardiovascular illness that is caused by prolonged ischemia. Circular RNAs (circRNAs) are concentrated in extracellular vesicles (EVs) and have been linked to cardiovascular ...
Jianbing Zhu, Zhaoyang Chen, Xiaoping Peng, Zeqi Zheng, Aiping Le, Junjie Guo, Leilei Ma, Hong-tao Shi, K. Yao, Shuning Zhang, Junbo Ge, Zhenzhong Zheng, Qian Wang   +12 more
semanticscholar   +1 more source