Results 161 to 170 of about 2,158,309 (327)

Population Pharmacokinetics of Dupilumab in Adults, Adolescents, and Children With Eosinophilic Esophagitis

Clinical Pharmacology &Therapeutics, EarlyView.
Dupilumab, a fully human monoclonal antibody that blocks key drivers of type 2 inflammation, is approved across 8 diseases, including eosinophilic esophagitis. Subcutaneous dupilumab 300 mg weekly improved outcomes vs. placebo in adults (aged ≥ 18 years) and adolescents (aged ≥ 12 to < 18 years) during the phase III LIBERTY EoE TREET study (NCT03633617)
Jenny‐Hoa Nguyen, Mirna Chehade, Evan S. Dellon, Allen Radin, Jason Chittenden, Mohamed A. Kamal, Margee Louisias, Christine Xu, Matthew P. Kosloski   +8 more
wiley   +1 more source

Expedition 379 methods [PDF]

, 2021
K. Gohl, J.S. Wellner, A. Klaus, T. Bauersachs, S.M. Bohaty, M. Courtillat, E.A. Cowan, M.A. De Lira Mota, M.S.R. Esteves, J.M. Fegyveresi, T. Frederichs, L. Gao, A.R. Halberstadt, C. Hillenbrand, K. Horikawa, M. Iwai, J. Kim, T.M. King, J.P. Klages, S. Passchier, M.L. Penkrot, J.G. Prebble, W. Rahaman, B.T.I. Reinardy, J. Renaudie, D.E. Robinson, R.P. Scherer, C.S. Siddoway, L. Wu, M. Yamane   +29 more
openaire   +1 more source

Where Tech Meets the SDGs: A Supply‐Chain Process Map for Sustainability Management

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study investigates how advanced technologies support Sustainable Development Goals (SDGs) within supply chain management (SCM) through a structured analysis of 4448 sustainable practices. By integrating perspectives from sustainability‐oriented innovation (SOI) and contingent dynamic capabilities, the research conceptualizes technology ...
Vincenzo Varriale, Antonello Cammarano, Moacir Godinho‐Filho   +2 more
wiley   +1 more source

Bridging Theory and Prediction: A Hybrid SEM and Machine Learning Approach to Optimize Lean Construction for Megaproject Sustainability in China

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT Construction megaprojects, large‐scale, complex, and capital‐intensive, are particularly prone to inefficiencies, cost overruns, delays, and environmental degradation due to fragmented workflows, stakeholder misalignment, and resource intensity.
Abdelazim Ibrahim, Tarek Zayed, Zoubeir Lafhaj, Ahmed Maged, Ahmed Farouk Kineber, Jingchao Yang   +5 more
wiley   +1 more source

Environmental, Social, and Governance (ESG) Performance and Equity Misvaluation: The Moderating Role of Country‐Level Factors

Corporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study explores how corporate environmental, social, and governance (ESG) performance affects equity misvaluation and how country‐level factors—national culture, environmental performance indicators, and world governance indicators (WGIs)—moderate the relationship between corporate ESG performance and misvaluation.
Xinyu Wang, Jun Xie, Hidemichi Fujii, Alexander Ryota Keeley, Shunsuke Managi   +4 more
wiley   +1 more source

Isomer Composition Assessment of Synthetic Phosphatidylethanol by Collision‐Induced and Ozone‐Induced Dissociation Mass Spectrometry

Drug Testing and Analysis, EarlyView.
This study examines the isomeric composition of PEth reference materials and compares it with the natural variation in isomer distribution found in blood samples. ABSTRACT The direct blood‐alcohol biomarker phosphatidylethanol (PEth), especially its most abundant analogue 1‐palmitoyl‐2‐oleoyl‐sn‐phosphatidylethanol (PEth 16:0/18:1) has gained ...
Matthias Bantle, Jackson O. T. Long, Samuel C. Brydon, Reuben S. E. Young, Stephen J. Blanksby, Wolfgang Weinmann, Marc Luginbühl   +6 more
wiley   +1 more source

Instability mechanism and failure characteristics of underground cavern in block system under the action of seismic waves

Deep Underground Science and Engineering, EarlyView.
Seismic waves with tensile stress, high amplitude, and low frequency are most likely to trigger block instability and sliding. Blocks with a single sliding surface are more prone to movement than those with multiple constraints, and roof‐positioned blocks are especially vulnerable to slide.
Xiao Wang, Jinxiao Liu, Gaoshuo Zhang, Wenxin Li, Changdi He   +4 more
wiley   +1 more source

Social Comparison and Its Association With Disordered Eating Symptoms: A Systematic Review and Meta‐Analysis

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Social comparison has been widely implicated in the etiology and maintenance of body dissatisfaction and eating disorders. At the same time, however, the magnitude of this relationship remains unclear, with existing studies varying widely in methodology, measurement, and sample characteristics.
Fidan Turk, Aysesu Bozdogan, Rachel Hughes, Phaedra Longhurst, Millie Chilvers, Ellen E. Fitzsimmons‐Craft   +5 more
wiley   +1 more source

Entropy‐Stabilized Pd/HEO Bifunctional Catalyst for Selective Aqueous‐Phase Hydrogenolysis of Cellulose to Ethylene Glycol

EcoEnergy, EarlyView.
An entropy‐stabilized Pd/HEO catalyst integrates Lewis acid and hydrogenation sites within a robust oxide–metal interface, enabling efficient and selective conversion of cellulose to ethylene glycol (68.3%) in water. ABSTRACT The selective conversion of cellulose into ethylene glycol (EG) under aqueous conditions is an attractive yet challenging route ...
Dandan Wang, Yuandong Cui, Wei Jia, Wei Jiang, Yuanming Zhang, Haoxi Ben, Xiaoli Yang   +6 more
wiley   +1 more source

Thermodynamic Mechanisms of Co‐S Bond Anchoring in Few‐Layered 1T‐MoS2 for Enhanced Capacitive Performance via Spin State Regulation and Ion Diffusion Kinetics

ENERGY &ENVIRONMENTAL MATERIALS, EarlyView.
The one‐pot hydrothermal prep of Co‐doped few‐layer 1T‐MoS2 shows Co‐S bonds stabilizing the 1T phase, enhancing supercapacitor performance. Few‐layered 1T‐MoS2 is highly promising for supercapacitor applications due to its wide interlayer spacing, high electrical conductivity, and abundant active sites.
Qingling Jia, Han Li, Shun Lu, Chuanyin Xiong, Yongxing Zhang   +4 more
wiley   +1 more source