Results 81 to 90 of about 5,662,897 (253)

Share - Publish - Store - Preserve. Methodologies, Tools and Challenges for 3D Use in Social Sciences and Humanities

open access: yes, 2020
"Through this White Paper, which gathers contributions from experts of 3D data as well as professionals concerned with the interoperability and sustainability of 3D research data, the PARTHENOS project aims at highlighting some of the current issues they
Consortium 3D SHS Team
core  

[Conférence]DARIAH VIRTUAL ANNUAL EVENT 2021: INTERFACES

open access: yes, 2021
"Digital interfaces enable communication between humans and machines, especially computers, by translating signals and providing capacity for the interpretation of information.
Consortium 3D SHS Team
core  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

open access: yesMolecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas   +16 more
wiley   +1 more source

diffcohesive: an open-source differentiable cohesive-zone finite element package for fracture simulation and interface-law identification

open access: yesSoftwareX
Ready-to-use open-source software for cohesive-zone modelling (CZM) of interfacial fracture is scarce, and setting up cohesive elements, mixed-mode laws, and path-following solvers from scratch requires considerable iteration.
Royson Donate Dsouza
doaj   +1 more source

[Video] Scientists turn to 3D technology to help restore Notre Dame

open access: yes, 2021
"Scientists have enlisted the help of 3D imaging technology to restore Notre Dame to its former glory. A digital team from France's National Centre for Scientific Research has been working on the site for the past two years since the cathedral was ...
Consortium 3D SHS Team
core  

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

open access: yesMolecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi   +6 more
wiley   +1 more source

Reflexive Perplexities: The Virtual Camera in ‘She’s Not There’

open access: yesInternational Journal of Film and Media Arts, 2017
We report on the conception, production and delivery of the live music, live performance, 3D animated project She’s Not There that opened the CILECT congress in Brisbane in November 2016.
Peter Moyes, Louise Harvey
doaj  

Investigating the fracture behavior of 3D printed orthotropic porous materials under mixed-mode I/II loading

open access: yesPolymer Testing
Porous materials possess holes, voids, and free space within their structures. Typically, these pores exhibit a random shape, size, and orientation distribution. The complexities in the structure affect the overall properties of these materials.
Seyed Mohammad Javad Tabatabaee   +1 more
doaj   +1 more source

Synthesis and AChE-Inhibitory Activity of New Benzimidazole Derivatives

open access: yesMolecules, 2019
Alzheimer’s disease (AD), one of the main causes of aged dementia, is a progressive and degenerative neurological disorder characterized by loss of cognition and memory.
Ulviye Acar Cevik   +6 more
doaj   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

open access: yesMolecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez   +5 more
wiley   +1 more source

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