Results 101 to 110 of about 5,698,007 (273)

Three-dimensional numerical analysis of a dam-break using OpenFOAM

Труды Института системного программирования РАН, 2018
This paper presents a 3D numerical analysis of flow field patterns in a dam break laboratory scale by applying the numerical code based on Finite Volume Method (FVM), OpenFOAM.
E. Sánchez-Cordero, M. Gómez, E. Bladé   +2 more
doaj   +1 more source

Developing Interaction 3D Models for E-Learning Applications [PDF]

, 2009
Some issues concerning the development of interactive 3D models for e-learning applications are considered. Given that 3D data sets are normally large and interactive display demands high performance computation, a natural solution would be placing the ...
Robinson, Alan, Rodrigues, Marcos
core  

Genetic attenuation of ALDH1A1 increases metastatic potential and aggressiveness in colorectal cancer

Molecular Oncology, EarlyView.
Aldehyde dehydrogenase 1A1 (ALDH1A1) is a cancer stem cell marker in several malignancies. We established a novel epithelial cell line from rectal adenocarcinoma with unique overexpression of this enzyme. Genetic attenuation of ALDH1A1 led to increased invasive capacity and metastatic potential, the inhibition of proliferation activity, and ultimately ...
Martina Poturnajova, Zuzana Kozovska, Ondrej Pos, Kristina Pavlov, Sachin Gulati, Peter Makovicky, Kristina Jakic, Monika Burikova, Eva Sedlackova, Barbora Svitkova, Silvia Tyciakova, Vojtech Bystry, Nicolas Blavet, Boris Tichy, Matej Hrnciar, Jaroslav Budis, Miroslav Tomas, Peter Dubovan, Georgina Kolnikova, Veronika Repaska, Nikoleta Mojzesova, Eva Zomborska, Daniel Pindak, Michal Mego, Tomas Szemes, Miroslava Matuskova   +25 more
wiley   +1 more source

Nanorobotics : a Newer Platform for Molecular Diagnose

Nano Biomedicine and Engineering, 2011
The present era of nanotechnology has reached to a stage where scientist are able to develop and programme complex machines that are built at molecular level which can work inside the patient body. One such challenge is a nanorobot, which once thought to
R Vijayakumar, S Jagannathan, P Rahul Gandhi, S Chaansha   +3 more
doaj   +1 more source

Dimethyl fumarate combined with cisplatin at subcytotoxic doses sensitizes cervical cancer toward ferroptosis and apoptosis through GSH restriction and p53 (re)activation

Molecular Oncology, EarlyView.
Dimethyl fumarate (DMF) reduces growth of HPV‐positive cervical cancer spheroids and induces ferroptosis in cervical cancer cells via blocking SLC7A11/Glutathione (GSH) axis. Combination of subcytotoxic doses of DMF and cisplatin (CDDP) further suppresses spheroid growth and drives cell death in 2D culture models.
Carolina Punziano, Giuseppina Minopoli, Simona Romano, Laura Marrone, Katia Aquilano, Maria Lina Tornesello, Raffaella Faraonio   +6 more
wiley   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Correlation of Computed Tomography Scans and Three-Dimensional Reconstructions with Macroscopic Cross-Sectional Anatomy of the Feline Head (Native Egyptian breed Cats) [PDF]

Journal of Applied Veterinary Sciences
This work aims to create three-dimensional (3D) models representing the anatomical configuration of the domestic cat head by using the prepared slides of the cross-sections at sequential levels and correlated images of a computed tomography (CT) scan. In
Abdelmohsen B.A., Sary R.G., Abou-Elela Y.S., Daghash S.M., Farag F.M.   +4 more
doaj   +1 more source

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

A Blow-Up Criterion for the 3D Euler Equations Via the Euler-Voigt Inviscid Regularization

, 2015
We propose a new blow-up criterion for the 3D Euler equations of incompressible fluid flows, based on the 3D Euler-Voigt inviscid regularization. This criterion is similar in character to a criterion proposed in a previous work by the authors, but it is ...
Larios, Adam, Titi, Edriss S.
core  

COMP–PMEPA1 axis promotes epithelial‐to‐mesenchymal transition in breast cancer cells

Molecular Oncology, EarlyView.
This study reveals that cartilage oligomeric matrix protein (COMP) promotes epithelial‐to‐mesenchymal transition (EMT) in breast cancer. We identify PMEPA1 (protein TMEPAI) as a novel COMP‐binding partner that mediates EMT via binding to the TSP domains of COMP, establishing the COMP–PMEPA1 axis as a key EMT driver in breast cancer.
Konstantinos S. Papadakos, Gilar Gorji‐bahri, Lejla Gradjan, Julia Zajac, Kacper Gil, Yvonne Thokozile Nduku, Anna M. Blom   +6 more
wiley   +1 more source