Results 81 to 90 of about 3,388,278 (296)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

open access: yesFEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta   +3 more
wiley   +1 more source

Les rencontres du Consortium 3D SHS Création -Usage scientifique - Conservation des données 3D

open access: yes, 2020
La multiplication des initiatives autour de la création, des usages et de la conservation des données 3D dans les sciences humaines et sociales montrent une réelle nécessité de se coordonner afin de définir des standards dans les usages, les ...
Consortium 3D SHS Team
core  

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

aLTAG3D, un logiciel pour l'archivage 3D

open access: yes, 2020
" aLTAG3D est un logiciel libre offrant une interface utilisateur simple et efficace pour la génération d'archive à long terme de projets 3D. L'archive générée est immédiatement compatible avec les services du CINES
Consortium 3D SHS Team
core  

Il laser a scansione per la documentazione dell'edificato

open access: yesGEOmedia, 2016
Il laser a scansione per la documentazione dell ...
Luigi Colombo, Barbara Marana
doaj  

Nutrient/TOR signaling controls adipose mitochondrial transcription factor A (TFAM) to regulate organismal growth in Drosophila

open access: yesFEBS Letters, EarlyView.
Animals must match their growth rate to available nutrients. We show that in Drosophila larvae, the nutrient‐sensing TOR kinase controls growth by regulating levels of TFAM, a key regulator of mitochondrial function, in the adipose tissue. When nutrients are abundant, high TOR activity suppresses TFAM, lowering mitochondrial bioenergetic activity and ...
Shrivani Sriskanthadevan‐Pirahas   +4 more
wiley   +1 more source

[Video] Scientists turn to 3D technology to help restore Notre Dame

open access: yes, 2021
"Scientists have enlisted the help of 3D imaging technology to restore Notre Dame to its former glory. A digital team from France's National Centre for Scientific Research has been working on the site for the past two years since the cathedral was ...
Consortium 3D SHS Team
core  

Dal LiDAR Mapping Forum di Amsterdam un report di buon auspicio per il mercato del 2015

open access: yesGEOmedia, 2015
Si è conclusa da poco più di un mese la European Lidar Mapping Forum la conferenza dedicata al Laser Scanning e all’imaging realizzata nell’accog liente spazio del Passenger Terminal di Amsterdam. A report by the European Lidar Mapping Forum.
Renzo Carlucci
doaj  

Peripheral lysosomes recruit PLEKHG3 to focal adhesions and restrain protrusion dynamics

open access: yesFEBS Letters, EarlyView.
Proximity‐dependent labeling at the LAMTOR complex revealed the Rho GEF PLEKHG3 as a lysosome‐proximal protein directing the study toward the influence of lysosome positioning on actin dynamics and cell motility. We show that PLEKHG3 colocalizes with lysosomes at focal adhesion sites and observe that forced peripheral dispersion of lysosomes hinders ...
Rainer Ettelt   +8 more
wiley   +1 more source

L’archivage pérenne des modèles numériques 3D pour les SHS

open access: yes, 2020
Ce document est la formalisation d’une étape de la réflexion consacrée à l'archivage des données 3D mené au sein du consortium 3D SHS en collaboration avec Huma-Num et le CINES.
Consortium 3D SHS Team
core  

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