Results 41 to 50 of about 221,450 (309)

Approximate Bayesian Image Interpretation using Generative Probabilistic Graphics Programs [PDF]

open access: yes, 2013
The idea of computer vision as the Bayesian inverse problem to computer graphics has a long history and an appealing elegance, but it has proved difficult to directly implement.
Kulkarni, Tejas D.   +3 more
core   +4 more sources

Development of visible light‐sensitive human neuropsin (OPN5) via single amino acid substitution

open access: yesFEBS Letters, EarlyView.
The present study determines a key amino acid residue, Lys91, for defining UV sensitivity of human OPN5. Heterologous action spectroscopy of the wild type and K91 mutants of OPN5 in HEK293T cells reveals that substitution of Lys91 with neutral (alanine) or acidic amino acids (glutamic or aspartic acids) causes substantial shifts in spectral sensitivity
Yusuke Sakai   +2 more
wiley   +1 more source

Pengembangan Fast Render Objek Grafis Menggunakan Shader dan Non-Shader Berbasis WebGL dari Primitive Object untuk Membuat Raw Metaverse Material Objek Skybox 3D di Filkom UB

open access: yesJurnal Teknologi Informasi dan Ilmu Komputer, 2022
Dalam perkembangannya, teknologi komputer telah mengalami peningkatan yang cukup signifikan. Seiring berkembangnya komputer sekarang, setiap pengembang dapat merekayasa suatu objek di dunia maya.
Imam Cholissodin   +5 more
doaj   +1 more source

The form of sound through hybrid materials [PDF]

open access: yes, 2016
The poster was presented at the SIGGRAPH '16 Special Interest Group on Computer Graphics and Interactive Techniques Conference, Anaheim, CA — July 24 - 28, 2016.
Ferrarello L.   +3 more
core   +1 more source

Escape from TGF‐β‐induced senescence promotes aggressive hallmarks in epithelial hepatocellular carcinoma cells

open access: yesMolecular Oncology, EarlyView.
Chronic TGF‐β exposure drives epithelial HCC cells from a senescent state to a TGF‐β resistant mesenchymal phenotype. This transition is characterized by the loss of Smad3‐mediated signaling, escape from senescence, enhanced invasiveness and metastatic potential, and upregulation of key resistance modulators such as MARK1 and GRM8, ultimately promoting
Minenur Kalyoncu   +11 more
wiley   +1 more source

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

Fast 3D solvers for interactive computational mechanics

open access: yesJournal of Mathematics in Industry
While interactive simulations have been mostly limited to Computer Graphics applications, new generations of Graphics Processing Units (GPUs) allow the realization of industrial-grade interactive 3D physics simulations.
Stefan Gavranovic   +3 more
doaj   +1 more source

Pintura y escultura digital 3d con ZBrush aplicada a la Arqueología

open access: yesVirtual Archaeology Review, 2011
The technology 3D is every day developing by leaps and bounds. Programs like 3D Studio Max, Lightwave, Maya, ZBrush … allow to model in 3D with constant innovations in its palettes of tools and its render systems and resolution.
Marta Ángeles Estalayo Moreno
doaj   +1 more source

The anticancer effect of the HDAC inhibitor belinostat is enhanced by inhibitors of Bcl‐xL or Mcl‐1 in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
The pan‐HDAC inhibitor belinostat increases the expression of the pro‐apoptotic proteins Bim, Puma, and Noxa and induces apoptosis in ovarian cancer cell lines and patient‐derived tumor organoids when used at high concentrations. Moreover, inhibiting the anti‐apoptotic proteins Bcl‐xL or Mcl‐1 sensitizes these preclinical models to the cytotoxic effect
Cécilia Thomine   +10 more
wiley   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

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