Results 151 to 160 of about 668,339 (308)
Culture 2D et 3D des cellules stromales mésenchymateuses équines d’origine musculaire : méthodes d’amplification, de conservation et propriétés immunomodulatrices [PDF]
Les cellules stromales mésenchymateuses (MSCs) présentent des propriétés immunomodulatrices et ont, de ce fait, suscité un vif interêt en thérapie cellulaire pour les pathologies inflammatoires aiguës ou dégénératives et auto-immunes.
Duysens, Julien
core
FEBS Open Bio, EarlyView.Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis
FEBS Open Bio, EarlyView.Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho +4 more
wiley +1 more source
Comparative Analysis of Mobile 3D Scanning Technologies for Design, Manufacture of Interior and Exterior Tensile Material Structures and Canvasman Ltd. Case Study [PDF]
This report aimed to investigate mobile 3D Scanning technologies to improve the 3D data capture and efficiency into Canvasman’s CAD design and manufacturing processes with focus on accurate resolution. The Santander funded Collaborative Venture Fund (CVF)
Ball, Andrew +3 more
core
FEBS Open Bio, EarlyView.A novel signature integrating genome‐wide analysis with clinical factors predicts recurrence in stage II colorectal cancer and enables a new risk stratification to guide postoperative adjuvant chemotherapy. Clinical risk stratification for postoperative recurrence in patients with pathological stage II (pStage II) colorectal cancer (CRC) is essential ...
Mayuko Otomo +7 more
wiley +1 more source
Report on the experimental results of 3D cultures of cancer stem cell-enriched cultures.
openaire +1 more source
A Novel 3D Culture System for the study of mechanisms of anti-cancer drug resistance in vitro [PDF]
, 2012 A Novel 3D Culture System for the study of mechanisms of anti-cancer drug resistance in ...
孙广炜 +5 more
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FEBS Open Bio, EarlyView.Pharmacological inhibition of PERK in a DEN‐induced mouse model of liver cancer does not reduce tumor burden but alters cellular stress signaling. Despite blocking PERK activity, downstream stress responses, including CHOP expression, remain active, suggesting compensatory mechanisms within the unfolded protein response that may influence tumor ...
Ada Lerma‐Clavero +5 more
wiley +1 more source
A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
RoundMi: A quantitative method to analyze mitochondrial morphology in mitotic cells
FEBS Open Bio, EarlyView.RoundMi is a workflow for rapid analysis of mitochondrial morphology in mitotic cells. By combining adaptive preprocessing with automated segmentation and quantification, it enables accurate measurements from single focal plane images, reducing acquisition time and computational demands while remaining compatible with high‐throughput fixed and live ...
Elmira Parvindokht Bararpour +2 more
wiley +1 more source