Results 191 to 200 of about 395,775 (261)

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Real-time 3D ultrasound in augmented reality accelerates training and narrows novice-expert performance gaps. [PDF]

Commun Eng
Hou JF, Viswanath S, Dilibal C, Wu B, Shende T, Dagdeviren C.   +5 more
europepmc   +1 more source

SPG4 and Dementia: Expanding the Clinical Spectrum

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Hereditary spastic paraplegia (HSP) is a group of disorders characterized by progressive spasticity and lower limb weakness, with mutations in SPG4/SPAST being the most common cause. Detailed studies and clinical and molecular comparisons across different populations are missing.
Emanuele Panza, Arun Meyyazhagan, Eliseo Picchi, Gustavo Ribas, Ingrid Faber, Ryosuke Miyamoto, Preethi Basavaraju, Paolo Eusebi, Haripriya Kuchi Bhotla, Mario Stasi, Fabrizio Gaudiello, Francesco Patti, Filippo Maria Santorelli, Marcondes Cavalcante França Jr, José Luiz Pedroso, Orlando Graziani Povoas Barsottini, Hélio Afonso Ghizoni Teive, Peter Henry St George‐Hyslop, Toshitaka Kawarai, Antonio Orlacchio   +19 more
wiley   +1 more source

Febrile Temperature Augments Ring-stage Plasmodium falciparum Adhesion to Brain Endothelial Cells. [PDF]

J Infect Dis
Joof F, Hu R, Seydel KB, Cohee LM, Zheng Y, Smith JD.   +5 more
europepmc   +1 more source

The multimodal display of rattlesnakes is a deterring signal that works best with sympatric species. [PDF]

PLoS One
Da Cunha O, Mead JJ, Horne LM.
europepmc   +1 more source

Laparoscopic Distal Gastrectomy Using Multimodal Visualization in a Patient with Situs Inversus Totalis and a Duplicated Portal Vein: A Case Report. [PDF]

Surg Case Rep
Otani T, Kichiraku T, Motoyama S, Kotanagi K, Satoyoshi R, Kudo K, Sawada T, Miyazawa H.   +7 more
europepmc   +1 more source

Detection of mitochondrial bioenergetics using a novel bimodal 3D microelectrode array (MEA)-based biosensor. [PDF]

Microsyst Nanoeng
James RK, Hostios TC, Chang J, Patel A, Kashem FB, Johnson I, Manrique Castro J, Hickman J, Rajaraman S.   +8 more
europepmc   +1 more source

Characterizing pancreatic cancer-associated fibroblast heterogeneity in vascular microphysiological systems. [PDF]

Angiogenesis
Blackledge CW, Gullion S, McCabe I, Van NNK, Hariharan A, Luan C, Peng XL, Polacheck WJ, Yeh JJ, Shelton SE.   +9 more
europepmc   +1 more source

The Impact of the Orthodontic Forces on the Internal Resorptive Process for Intact Periodontium: A Finite Element Analysis. [PDF]

J Clin Med
Moga RA, Olteanu CD, Delean AG.
europepmc   +1 more source