Results 61 to 70 of about 389,519 (288)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, Volume 20, Issue 6, Page 1643-1660, June 2026.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Studies of three dimensional stagged-grid finite difference for Z-axis tipper electromagnetic numerical simulation

Frontiers in Earth Science
ZTEM (Z-Axis Tipper Electromagnetic System) is a frequency-domain airborne electromagnetic exploration method that utilizes natural field sources. This method is highly efficient and capable of probing great depths, making it widely applicable in the ...
Yu Wang, Junhao Qu, Tingting Chen, Shaohui Zhou, Yajun Li   +4 more
doaj   +1 more source

Adaption and GPU based parallelization of the code TEMDDD for the 3D modelling of CSEM data [PDF]

, 2010
The finite difference time domain code TEMDDD was modified for the 3D forward modeling of marine CSEM data. After changes in the code, which make it possible to create model geometries typically encountered in marine CSEM experiments, parts of the code
Heincke, Björn, Hölz, Sebastian, Jegen-Kulcsar, Marion, Moorkamp, Max, Sommer, Malte   +4 more
core  

Magnetic field diagnostics and spatio-temporal variability of the solar transition region

, 2013
Magnetic field diagnostics of the transition region from the chromosphere to the corona faces us with the problem that one has to apply extreme UV spectro-polarimetry.
A. Brković, B. Gudiksen, B. Gudiksen, B. Gudiksen, B.E. Woodgate, B.W. Lites, C.J. Schrijver, E. West, E.A. West, H. Lin, H. Peter, H. Peter, H. Peter, H. Peter, H. Peter, H. Peter, H. Peter, H. Peter, H. Peter, J. Trujillo Bueno, J. Štěpán, J.O. Stenflo, K. Kobayashi, K. Wilhelm, K.P. Dere, M.J. Hagyard, M.L. De Rosa, P. Zacharias, P. Zacharias, P.R. Young, R. Centeno, R.A. Harrison, R.A. Harrison, S. Bingert, S. Bingert, S.M. White, V.H. Hansteen, W. Henze Jr.   +37 more
core   +1 more source

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

Application of Realistic 3D Model in Building Prefabricated Nanomaterial Structure

International Journal of Analytical Chemistry, 2022
In order to solve the problem of 3D modeling in building assembly, an application of a 3D model based on the real scene in the building assembly structure is proposed.
Sihui Li
doaj   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

3D Gravity Modeling of Complex Salt Features in the Southern Gulf of Mexico

International Journal of Geophysics, 2016
We present a three-dimensional (3D) gravity modeling and inversion approach and its application to complex geological settings characterized by several allochthonous salt bodies embedded in terrigenous sediments.
Mauricio Nava-Flores, Carlos Ortiz-Aleman, Mauricio G. Orozco-del-Castillo, Jaime Urrutia-Fucugauchi, Alejandro Rodriguez-Castellanos, Carlos Couder-Castañeda, Alfredo Trujillo-Alcantara   +6 more
doaj   +1 more source

Similarity measure of sedimentary successions and its application in inverse stratigraphic modeling

Petroleum Science, 2017
This paper presents a unique and formal method of quantifying the similarity or distance between sedimentary facies successions from measured sections in outcrop or drilled wells and demonstrates its first application in inverse stratigraphic modeling. A
Taizhong Duan
doaj   +1 more source