Results 251 to 260 of about 14,483 (310)

The Development and Pilot Clinical Study of CD147 Targeted Antagonistic Peptide Probe for Tumor Imaging

Advanced Science, EarlyView.
This study establishes [68Ga]Ga‐DOTA‐AP9 as a first‐in‐human CD147‐targeted PET tracer with favorable safety and specific tumor uptake. Tracer accumulation correlates with CD147 expression in patients, enabling noninvasive quantification of CD147‐positive malignancies.
Xiaokun Ma, Rui Guo, Dongfeng Niu, Yufei Song, Zhenyao Zhang, Xiangxi Meng, Lili Mao, Haifeng Huang, Hua Zhu, Zhi Yang, Teli Liu   +10 more
wiley   +1 more source

A multidisciplinary and interoperable dataset to understanding the dialogue between humans and the environment in Southern Umbria, emphasising sustainable management and valorisation of cultural and landscape heritage. [PDF]

Data Brief
Carafa P, Cecconi N.
europepmc   +1 more source

Highly Biomimetic Ectodermal Epithelial Organoids for Epithelial Barrier Stimulation Assays

Advanced Science, EarlyView.
ABSTRACT Evaluating the potential toxicity of pharmaceuticals and biomaterials to ectodermal epithelia, such as the oral mucosa and skin, is indispensable in pre‐clinical assessments. However, this remains a challenge primarily owing to the lack of physiologically relevant and accurate screening models.
Yiming Chen, Yuman Li, Chenyu Deng, Leran Li, Zhewen Hu, Boon Chin Heng, Yuting Niu, Shiyu Sun, Min Gao, Xiaopei Chi, Ying He, Mingming Xu, Ying Huang, Xuliang Deng   +13 more
wiley   +1 more source

Elderly Activity Life-Space Envelopes (EASE): Development and Feasibility of a Comprehensive, Integrated Protocol for Life-Space Mobility Research in Population Health. [PDF]

JMIR Res Protoc
Ng YS, Zhao F, Ho LY, Tay L, Shum E, Latib A, Choo S, Chew S, Leong T, Pua YH, Yuen B, Joyce SC, Yang X, Chan A, Maulod A, Wong Y, Soh D, Balan RK, Low LL, Thumboo J, Ding YY, Hoenig HM, Lin S.   +22 more
europepmc   +1 more source

Large‐Scale Genomics Reveals Three‐Source Ancestry and Layered Adaptation to High Altitude in Tibetan Chickens

Advanced Science, EarlyView.
Whole‐genome analysis of 1,054 chickens reveals three ancestral sources (NWC, SYA, and SHF) with distinct temporal entry patterns into the Tibetan Plateau. Route‐specific selection scans, calibrated against a demographic null, suggest complementary functional enrichments—vascular homeostasis (NWC), calcium signaling and cardiac adaptation (SYA), and ...
Zongyi Zhao, Ruixue Nie, Hailu Fan, Tenzin Ngodroup, Li Zhu, Hongbin Pan, Bo Zhang, Hao Zhang   +7 more
wiley   +1 more source

Specialized aldo-keto reductases trigger complete degradation of mycotoxin deoxynivalenol. [PDF]

Nat Commun
He W, Xiong R, Zheng M, Zhang T, Zhang Y, Wang Q, Zhao C, Huang T, Liu Y, Tian Y, Tabl KM, Mao X, Li P, Feng G, Bai X, Liu Q, Yan W, Liao Y, Zhang J, Yin P, Wu A.   +20 more
europepmc   +1 more source

Single-cell structural biology with intracellular electron crystallography. [PDF]

Nat Commun
Bílá Š, Pinkas D, Khakurel K, Boger J, Bílý T, Hajdu J, Franta Z, de Diego Martinez I, Tuma R, Redecke L, Polovinkin V.   +10 more
europepmc   +1 more source

Urban traffic digital twin system development in unity. [PDF]

Sci Rep
Gong L, Ding M.
europepmc   +1 more source

Oncological value of MRI in brain metastasis: exploring the potential of combining post-contrast T1 TSE (SPACE) and T1 GRE (MPRAGE) for stereotactic radiosurgery planning and surveillance. [PDF]

J Neurooncol
Uysal E, Reinhardt P, Schmidhalter D, Wagner F, Ermiş E.   +4 more
europepmc   +1 more source

Charting cell-type-specific positive genetic interaction at single-cell resolution for lung adenocarcinoma. [PDF]

NPJ Precis Oncol
Chen B, Liu M, Dong Q, Lv C, Liu K, Han H, Wang L, Zhang N, Zhao W, Lv J, Gu Y.   +10 more
europepmc   +1 more source