Results 101 to 110 of about 2,162,733 (357)

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Obesity alters the fitness of peritumoral adipose tissue, exacerbating tumor invasiveness in renal cancer through the induction of ADAM12 and CYP1B1

Molecular Oncology, EarlyView.
Tumor microenvironment drives cancer formation and progression. We analyzed the role of human cancer‐associated adipocytes from patients with renal cell carcinoma (RCC) stratified as lean, overweight, or obese. RNA‐seq demonstrated that, among the most altered genes involved in the tumor–stroma crosstalk, are ADAM12 and CYP1B1, which were proven to be ...
Sepehr Torabinejad, Caterina Miro, Annarita Nappi, Francesco Del Giudice, Annunziata Gaetana Cicatiello, Serena Sagliocchi, Lucia Acampora, Federica Restolfer, Melania Murolo, Emery Di Cicco, Federico Capone, Ciro Imbimbo, Monica Dentice, Felice Crocetto   +13 more
wiley   +1 more source

3D Printing of Molecular Models

Journal of Biocommunication, 2016
Physical models have a long and important role in exploring and communicating scientific and medical concepts and structures. One of the earliest physical scientific visualizations was the orrery, a mechanical model of the solar system, which first appeared in Greece around 150 BC.
Arthur J. Olson, Adam Gardner
openaire   +4 more sources

Generative VoxelNet: Learning Energy-Based Models for 3D Shape Synthesis and Analysis [PDF]

arXiv, 2020
3D data that contains rich geometry information of objects and scenes is valuable for understanding 3D physical world. With the recent emergence of large-scale 3D datasets, it becomes increasingly crucial to have a powerful 3D generative model for 3D shape synthesis and analysis.
arxiv  

Addressing persistent challenges in digital image analysis of cancer tissue: resources developed from a hackathon

Molecular Oncology, EarlyView.
Large multidimensional digital images of cancer tissue are becoming prolific, but many challenges exist to automatically extract relevant information from them using computational tools. We describe publicly available resources that have been developed jointly by expert and non‐expert computational biologists working together during a virtual hackathon
Sandhya Prabhakaran, Clarence Yapp, Gregory J. Baker, Johanna Beyer, Young Hwan Chang, Allison L. Creason, Robert Krueger, Jeremy Muhlich, Nathan Heath Patterson, Kevin Sidak, Damir Sudar, Adam J. Taylor, Luke Ternes, Jakob Troidl, Xie Yubin, Artem Sokolov, Darren R. Tyson   +16 more
wiley   +1 more source

Interoperability of photogrammetry in 3D modeling: documentation, research and dissemination in the archaeological site of Jamila

Virtual Archaeology Review, 2015
This paper intends to be a sample, both theoretical and practical, of a protocol for the use of photogrammetric resources when generating a three-dimensional archaeological model.
Pedro R. Moya-Maleno, Juan Tormejón Valdelomar, David Vacas Madrid, Rocío Losa Sánchez   +3 more
doaj   +1 more source

Integration of single‐cell and bulk RNA‐sequencing data reveals the prognostic potential of epithelial gene markers for prostate cancer

Molecular Oncology, EarlyView.
Prostate cancer is a leading malignancy with significant clinical heterogeneity in men. An 11‐gene signature derived from dysregulated epithelial cell markers effectively predicted biochemical recurrence‐free survival in patients who underwent radical surgery or radiotherapy.
Zhuofan Mou, Lorna W. Harries
wiley   +1 more source

Multidisciplinary study for the documentation of the Ramintoja Church in Vilnius. Development of 3D models for virtualization and historical reconstruction.

Disegnare con, 2021
The paper intends to present the results of a multidisciplinary project concerning the architectural documentation and the three-dimensional virtualization of the Ramintoja Church in Vilnius (Lithuania), conducted through morphological-metric, diagnostic
Stefano Bertocci, Andrea Arrighetti, Andrea Lumini, Federico Cioli   +3 more
doaj  

Etoposide‐induced cancer cell death: roles of mitochondrial VDAC1 and calpain, and resistance mechanisms

Molecular Oncology, EarlyView.
The complex mode of action of the topoisomerase II inhibitor etoposide in triggering apoptosis involves several mechanisms: overexpression of the mitochondrial protein VDAC1, leading to its oligomerization and formation of a large channel that mediates the release of pro‐apoptotic protein; and overexpression of the apoptosis regulators p53, Bax, and ...
Aditya Karunanithi Nivedita, Varda Shoshan‐Barmatz   +1 more
wiley   +1 more source

Learning Efficient Point Cloud Generation for Dense 3D Object Reconstruction

, 2017
Conventional methods of 3D object generative modeling learn volumetric predictions using deep networks with 3D convolutional operations, which are direct analogies to classical 2D ones.
Kong, Chen, Lin, Chen-Hsuan, Lucey, Simon   +2 more
core   +1 more source