Results 51 to 60 of about 2,403,301 (299)

Urokinase-type plasminogen activator (uPA) regulates invasion and matrix remodelling in colorectal cancer

open access: yesMatrix Biology Plus, 2023
Background: Cancer cells remodel their local physical environment through processes of matrix reorganisation, deposition, stiffening and degradation.
Auxtine Micalet   +8 more
doaj   +1 more source

Nonintrusive coupling of 3D and 2D laminated composite models based on finite element 3D recovery

open access: yes, 2014
In order to simulate the mechanical behavior of large structures assembled from thin composite panels, we propose a coupling technique which substitutes local 3D models for the global plate model in the critical zones where plate modeling is inadequate ...
Allix, Olivier   +3 more
core   +4 more sources

Fitting 3D Morphable Models using Local Features [PDF]

open access: yes, 2015
In this paper, we propose a novel fitting method that uses local image features to fit a 3D Morphable Model to 2D images. To overcome the obstacle of optimising a cost function that contains a non-differentiable feature extraction operator, we use a ...
Christmas, William   +4 more
core   +2 more sources

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

3D Modeling

open access: yes
Content: report on the choice of the 3D representation and on the 3D mapping activities. A focus of the performance assessment will be on on accuracy, reliability, and completeness of the reconstructed 3D structure both in terms of usable result for human operators as well as usage in the robotic navigation tasks.
Sander Münster   +12 more
openaire   +3 more sources

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

The planar cell polarity protein Vangl2 interacts with the PDZ‐domains of Scribble but not with a unique PDZ‐like domain in Inturned

open access: yesFEBS Letters, EarlyView.
Structural and biochemical characterisations show that the planar cell polarity (PCP) protein Inturned harbours a unique PDZ‐like domain that does not bind canonical PDZ‐binding motifs (PBMs) like that of another PCP protein Vangl2. In contrast, the apical‐basal polarity protein Scribble contains four PDZ domains that bind Vangl2, but one PDZ domain ...
Stephan Wilmes   +4 more
wiley   +1 more source

String tension in gonihedric 3D Ising models [PDF]

open access: yes, 1997
For the 3D gonihedric Ising models defined by Savvidy and Wegner the bare string tension is zero and the energy of a spin interface depends only on the number of bends and self-intersections, in antithesis to the standard nearest-neighbour 3D Ising ...
Baig M   +18 more
core   +2 more sources

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

The Cultural Value of the Copy in the Museum Domain

open access: yesimg journal, 2021
The essay aims to analyse past and present methods of reality simulation critically. It proposes a non-exhaustive classification of 2D and 3D digital artefacts mainly concerning the cultural heritage field and the museum domain, ranging from ...
Massimiliano Lo Turco   +2 more
doaj   +1 more source

Home - About - Disclaimer - Privacy