Results 121 to 130 of about 24,701,544 (313)

Numerical verification of fracture toughness values for very thin 3D printed polyamide samples

Acta Polytechnica CTU Proceedings
This researche presents an experimental and numerical analysis of the mechanical properties of very thin polyamide (PA12) samples fabricated by 3D printing with selective laser sintering (SLS).
Petr Bočan, Aleš Jíra
doaj   +1 more source

Inhibition of cyclin‐dependent kinases 12/13 using CT7439 as a treatment for colorectal cancer with CDK12 upregulation

Molecular Oncology, EarlyView.
The proposed mechanism of action for the CDK12/13 inhibitor and cyclin K degrader, CT7439. CDK12/13 inhibition interrupts transcription elongation, leading to increased DNA damage that results in cell death. This agent is a potentially novel treatment option for patients with colorectal cancer. Created in BioRender. Cyclin‐dependent kinase (CDK) 12 and
Wylie K. Watlington, Divya L. Dayanidhi, Mohammad Zokaasadi, John B. Mantyh, Pelumi D. Olawuni, Gabrielle Rupprecht, Jeremy M. Force, Shannon McCall, Ashwani K. Bahl, David S. Hsu, Jason A. Somarelli   +10 more
wiley   +1 more source

Meshless methods: theory and application in 3D fracture modelling with level sets [PDF]

, 2010
Accurate analysis of fracture is of vital importance yet methods for effetive 3D calculations are currently unsatisfactory. In this thesis, novel numerical techniques are developed which solve many of these problems. This thesis consists two major parts:
ZHUANG, XIAOYING
core  

Product, process, property, and performance (PPPP) relationship of 3D-Printed polymers and polymer composites: Numerical and experimental analysis

Advanced Industrial and Engineering Polymer Research
Understanding the external and internal factors during an additive manufacturing (AM) process is crucial, as they can significantly affect the final product's performance.
Ans Al Rashid, Shoukat Alim Khan, Muammer Koç   +2 more
doaj   +1 more source

In vitro and in silico modelling of ROS1‐positive non‐small cell lung cancer reveals fusion‐dependent tyrosine kinase inhibitor responses

Molecular Oncology, EarlyView.
Drug resistance limits treatment success in a subset of lung cancers driven by ROS1 gene alterations. Using patient‐derived cells and computer simulations, we studied three key mutations and how they affect five targeted drugs. The mutations reduced drug effectiveness in different ways by altering protein structure and behavior.
Farhan Ul Haq, Marc Terrones, Felicia Rodrigues Fortes, Anne Schepers, Alessia Denis, Christophe Deben, Ken Op de Beeck, Guy Van Camp, Geert Vandeweyer   +8 more
wiley   +1 more source

Numerical Analysis Center Notes and Comments, April 1967

, 1967
University of Minnesota. Numerical Analysis Center. (1967). Numerical Analysis Center Notes and Comments, April 1967.
University of Minnesota. Numerical Analysis Center
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[Video] Scientists turn to 3D technology to help restore Notre Dame

, 2021
"Scientists have enlisted the help of 3D imaging technology to restore Notre Dame to its former glory. A digital team from France's National Centre for Scientific Research has been working on the site for the past two years since the cathedral was ...
Consortium 3D SHS Team
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Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

Molecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park, Kyongman An, Gyeonghwa Kim, Soo‐Nyun Choi, Hong‐Ki Lee, Keun Hur, Kyu‐Shik Jeong   +6 more
wiley   +1 more source

Apport critique sur les matériels et logiciels 3D : Synthèse des outils et des technologies 3D

, 2020
"Le regroupement des différents partenaires du Consortium 3D SHS (Huma-Num) a été l’occasion de partager l’expertise et le savoir-faire - tant théorique que pratique - de ses membres, sur les modalités de production d’un objet numérique patrimonial.
Consortium 3D SHS Team
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NUMERICAL ANALYSIS OF NAPOLEON ' S THEOREM IN 3D

Discussion of Napoleon-s theorem in 3D using numerical methods.
openaire   +1 more source