Results 81 to 90 of about 24,701,544 (313)
Jixie chuandong, 2007 Exact computation and analysis of the workspace volume of robot manipulators is very important for its optimum design and application. A numerical method based on random probability is used to generate the workspaces of 3D robot, according to the ...
曹毅, 于心俊, 杨冠英
doaj
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
3D printing of TPMS microlattice: indentation characterisation and numerical analysis
Virtual and Physical PrototypingMechanical metamaterials are emerging as an important tool in many engineering applications, where microarchitectured lattices have advantages of high strength-to-weight ratios, energy absorption capabilities and versatility in designed mechanical ...
William S. Harley +6 more
doaj +1 more source
Metastatic niche shaped by host factors influences disseminated cancer cell fate
FEBS Letters, EarlyView.Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward +2 more
wiley +1 more source
Analysis of gradual dike bend breach through 3D numerical simulation
Shuili Shuiyun Gongcheng XuebaoTo address challenges in understanding the comprehensive dynamics of dike bend breaches and the hydraulic features during breach evolution, a 3D numerical model is constructed utilizing FLOW-3D software, RNG k-ε turbulence model, and sediment model.
WANG Jiao +4 more
doaj +1 more source
Smaller is better: nanobodies meet NMR
FEBS Letters, EarlyView.Nanobodies are single‐domain antigen‐binding fragments derived from camelid heavy chain antibodies. Their small size, high stability, and exceptional specificity make nanobodies uniquely useful probes for NMR studies of protein dynamics, transient conformational states, and protein–protein interactions.
Oleg Y. Dmitriev
wiley +1 more source
L’archivage pérenne des modèles numériques 3D pour les SHS
, 2020 Ce document est la formalisation d’une étape de la réflexion consacrée à l'archivage des données 3D mené au sein du consortium 3D SHS en collaboration avec Huma-Num et le CINES.
Consortium 3D SHS Team
core
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Numerical Analysis Center Notes and Comments, October 1966
, 1966 University of Minnesota. Numerical Analysis Center. (1966). Numerical Analysis Center Notes and Comments, October 1966.
University of Minnesota. Numerical Analysis Center
core
Vocabulaire 3D - Lexique pour les Sciences Humaines et Sociales
, 2020 "Ce document est le résultat d’un effort continu pour permettre aux acteurs des SHS et ceux de la 3D d’interagir autour d’un vocabulaire commun. Ce lexique a pour but d’accompagner les différents livrables du consortium 3D.
Consortium 3D SHS Team
core