Results 111 to 120 of about 3,277,616 (304)

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

[Invited guests at the official opening of the Public Service Institute, Port Moresby, October, 1954] [picture] /

, 1954
Title supplied by donor.; Condition: good.; Inscription: 'Photograph by Papuan Prints Limited, Port Moresby' -- stamped on ...
Papuan Prints Limited, Port Moresby.
core  

Exploring the Impact of Using Patient-Specific 3D Prints during Consent for Skull Base Neurosurgery. [PDF]

J Neurol Surg B Skull Base, 2023
Mian SY, Jayasangaran S, Qureshi A, Hughes MA.   +3 more
europepmc   +1 more source

Castration‐resistant prostate cancer cells are addicted to the high activity of cyclin‐dependent kinase 2

Molecular Oncology, EarlyView.
We show that emergence of castration‐resistant prostate (CRPC) is associated with significant upregulation of cyclins that positively regulate cyclin‐dependent kinase 2 (CDK2) and concomitant downregulation of CDK4 cyclins. This renders CRPC cells dependent on the high activity of CDK2, and CDK2 inhibitors synergistically sensitize CRPC cells to both ...
Joyeeta Chatterjee, Alessia Marin, Shivani Yalala, Harri M. Itkonen   +3 more
wiley   +1 more source

[Associate Professor Ringrose, University of Queensland, delivering the keynote address, official opening of the Public Service Institute, Port Moresby, October 1954 [picture] /

, 1954
Inscription: 'Photograph by Papuan Prints Limited, Port Moresby' -- stamped on reverse.; Condition: good.; Title devised from information supplied by ...
Papuan Prints Limited, Port Moresby.
core  

Piezoelectric microphone via a digital light processing 3D printing process

Materials & Design, 2019
In nature sensors possess complex interlocking 3D structures and extremely localized material properties that allow processing of incredibly complex information in a small space.
Benjamin Tiller, Andrew Reid, Botong Zhu, José Guerreiro, Roger Domingo-Roca, Joseph Curt Jackson, J.F.C. Windmill   +6 more
doaj   +1 more source

Load Distribution on PET-G 3D Prints of Honeycomb Cellular Structures under Compression Load. [PDF]

Polymers (Basel), 2021
Basurto-Vázquez O, Sánchez-Rodríguez EP, McShane GJ, Medina DI.   +3 more
europepmc   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

[Video] Scientists turn to 3D technology to help restore Notre Dame

, 2021
"Scientists have enlisted the help of 3D imaging technology to restore Notre Dame to its former glory. A digital team from France's National Centre for Scientific Research has been working on the site for the past two years since the cathedral was ...
Consortium 3D SHS Team
core  

A Comparative Study of the Mechanical Properties of FDM 3D Prints Made of PLA and Carbon Fiber-Reinforced PLA for Thin-Walled Applications. [PDF]

Materials (Basel), 2021
Bochnia J, Blasiak M, Kozior T.
europepmc   +1 more source