Results 111 to 120 of about 104,995 (269)

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Rapid prototyping of cell culture microdevices using parylene-coated 3D prints. [PDF]

Lab Chip, 2021
O'Grady BJ, Geuy MD, Kim H, Balotin KM, Allchin ER, Florian DC, Bute NN, Scott TE, Lowen GB, Fricker CM, Fitzgerald ML, Guelcher SA, Wikswo JP, Bellan LM, Lippmann ES.   +14 more
europepmc   +1 more source

The Core-Collapse Supernova Explosion Mechanism

, 2016
The explosion mechanism of core-collapse supernovae is a long-standing problem in stellar astrophysics. We briefly outline the main contenders for a solution and review recent efforts to model core-collapse supernova explosions by means of multi ...
Müller, B.
core   +1 more source

Clinical performance of the urine‐based TERT promoter AbsoluteQ Digital PCR for non‐invasive detection of bladder cancer

Molecular Oncology, EarlyView.
A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel, Izabela Kubiak, Lena Rutkowska, Żaneta Kasprzyk, Łukasz Kępczyński, Michał Bednarek, Dariusz Sobieraj, Jacek Wilkosz, Piotr Kania, Adam Jędrzejczyk, Bogdan Kałużewski, Agnieszka Gach, Tadeusz Kałużewski   +12 more
wiley   +1 more source

Piezoelectric microphone via a digital light processing 3D printing process

Materials & Design, 2019
In nature sensors possess complex interlocking 3D structures and extremely localized material properties that allow processing of incredibly complex information in a small space.
Benjamin Tiller, Andrew Reid, Botong Zhu, José Guerreiro, Roger Domingo-Roca, Joseph Curt Jackson, J.F.C. Windmill   +6 more
doaj   +1 more source

Exploring the Impact of Using Patient-Specific 3D Prints during Consent for Skull Base Neurosurgery. [PDF]

J Neurol Surg B Skull Base, 2023
Mian SY, Jayasangaran S, Qureshi A, Hughes MA.   +3 more
europepmc   +1 more source

Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining

Molecular Oncology, EarlyView.
IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis, Jack V. Mills, Wojciech Niedzwiedz, Valentine M. Macaulay   +3 more
wiley   +1 more source

Load Distribution on PET-G 3D Prints of Honeycomb Cellular Structures under Compression Load. [PDF]

Polymers (Basel), 2021
Basurto-Vázquez O, Sánchez-Rodríguez EP, McShane GJ, Medina DI.   +3 more
europepmc   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

A Comparative Study of the Mechanical Properties of FDM 3D Prints Made of PLA and Carbon Fiber-Reinforced PLA for Thin-Walled Applications. [PDF]

Materials (Basel), 2021
Bochnia J, Blasiak M, Kozior T.
europepmc   +1 more source