Results 91 to 100 of about 104,995 (269)
Glioma cells mainly express the endothelin receptor EDNRB, while EDNRA is restricted to a perivascular tumor subpopulation. Endothelin signaling reduces glioma cell proliferation while promoting migration and a proneural‐to‐mesenchymal transition associated with poor prognosis. This pathway activates Ca2+, K+, ERK, and STAT3 signalings and is regulated
Donovan Pineau +36 more
wiley +1 more source
‘Figures in 3D’: Digital Perspectives on Cretan Bronze Age Figurines
The largest corpus of clay figurines from the Cretan Bronze Age comes from ritual mountain sites known as peak sanctuaries. In this paper, we explore how the ‛Figures in 3D’ project contributes to our understanding of these figurines, aiding in the study
Morris Christine +2 more
doaj +1 more source
The Proficiency of Experts [PDF]
Expert evidence plays a crucial role in civil and criminal litigation. Changes in the rules concerning expert admissibility, following the Supreme Court\u27s Daubert ruling, strengthened judicial review of the reliability and the validity of an expert ...
Garrett, Brandon L., Mitchell, Gregory
core +2 more sources
The Effect of the Radial Pressure Gradient in Protoplanetary Disks on Planetesimal Formation
The streaming instability (SI) provides a promising mechanism for planetesimal formation because of its ability to concentrate solids into dense clumps.
Bai +23 more
core +1 more source
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang +12 more
wiley +1 more source
By performing three-dimensional (3D) simulations that demonstrate the neutrino-driven core-collapse supernovae aided by the standing accretion shock instability (SASI), we study how the spiral modes of the SASI can have impacts on the properties of the ...
Ando +45 more
core +1 more source
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch +13 more
wiley +1 more source
A linear distribution of orbits in compact planetary systems?
We report a linear ordering of orbits in a sample of multiple extrasolar planetary systems with super-Earth planets. We selected 20 cases, mostly discovered by the Kepler mission, hosting at least four planets within \sim 0.5 au.
Gozdziewski, Krzysztof +2 more
core +1 more source
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric +10 more
wiley +1 more source
Automated 3D Printing in Libraries
This article highlights the creation of an automated 3D printed system created at a health sciences library at a large research university. As COVID-19 limited in-person interaction with 3D printers, a group of library staff came together to code a form ...
Brandon Patterson +2 more
doaj

