Results 101 to 110 of about 104,995 (269)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Development of tactile floor plan for the blind and the visually impaired by 3D printing technique

Journal of Graphic Engineering and Design, 2016
The aim of the research was to produce tactile floor plans for blind and visually impaired people for the use in the museum. For the production of tactile floor plans 3D printing technique was selected among three different techniques.
Raša Urbas, Matej Pivar, Urška Stankovič Elesini   +2 more
doaj  

Application of PolyJet 3D Printing in Production of Flexographic Printing Plates

Applied Sciences
The aim of this study was to investigate whether PolyJet technology, which uses rubber-like materials for printing and is known for its high resolution and performance, could be suitable for producing flexographic printing plates.
Joanna Izdebska-Podsiadły, Adam Lasecki
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Hydrogel-Assisted Double Molding Enables Rapid Replication of Stereolithographic 3D Prints for Engineered Tissue Design. [PDF]

ACS Appl Mater Interfaces, 2023
Simmons DW, Schuftan DR, Ramahdita G, Huebsch N.   +3 more
europepmc   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Using Own Algorithms to Increase the Quality and Fatigue Resistance of FDM Printing for Use in Drones and Small Aircraft

Fatigue of Aircraft Structures
The present article discusses the three-dimensional (3D) printing process in the fused deposition modeling (FDM) or the fused filament fabrication (FFF) technique using the author’s own philosophy of shaping the printing head path.
Szafran Krzysztof Stanisław, Jeziorek Łukasz Andrzej   +1 more
doaj   +1 more source

Novel Formulations Containing Fluorescent Sensors to Improve the Resolution of 3D Prints. [PDF]

Int J Mol Sci, 2022
Topa-Skwarczyńska M, Świeży A, Krok D, Starzak K, Niezgoda P, Oksiuta B, Wałczyk W, Ortyl J.   +7 more
europepmc   +1 more source

Correlated Signatures of Gravitational-Wave and Neutrino Emission in Three-Dimensional General-Relativistic Core-Collapse Supernova Simulations

, 2017
We present results from general-relativistic (GR) three-dimensional (3D) core-collapse simulations with approximate neutrino transport for three non-rotating progenitors (11.2, 15, and 40 Msun) using different nuclear equations of state (EOSs).
Hayama, Kazuhiro, Kotake, Kei, Kuroda, Takami, Takiwaki, Tomoya   +3 more
core   +1 more source