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The new paradigm in animal testing – “3Rs alternatives”
Regulatory Toxicology and PharmacologyRegulatory studies have revolutionised over time. Today, the focus has shifted from animal toxicity testing to non-animal for regulatory safety testing.
Johnson Stanslas
exaly +2 more sources
Planta Medica, 2023
The average age of the population is increasing worldwide, which has a profound impact on our society. This leads to an increasing demand for medicines and requires the development of new strategies to promote health during the additional years.
Martina Redl +2 more
semanticscholar +1 more source
The average age of the population is increasing worldwide, which has a profound impact on our society. This leads to an increasing demand for medicines and requires the development of new strategies to promote health during the additional years.
Martina Redl +2 more
semanticscholar +1 more source
Toward a common interpretation of the 3Rs principles in animal research
Lab animalMany scientific breakthroughs have depended on animal research, yet the ethical concerns surrounding the use of animals in experimentation have long prompted discussions about humane treatment and responsible scientific practice.
Jan Lauwereyns +21 more
semanticscholar +1 more source
In vitro characterization of anti-inflammatory activities of 3RS, 7R, 11R-phytanic acid
Journal of Dairy Research, 2023The aim of the research described here was to investigate the in vitro immunomodulatory effects of 3RS, 7R, 11R-phytanic acid (3RS-PHY) from the perspective of efficacy against autoimmune diseases. 3RS-PHY is a milk component with strong agonist activity
T. Nakanishi +6 more
semanticscholar +1 more source
Asia Pacific Journal of Education
Generative Artificial Intelligence (AI)’s emergence is viewed as a disruptive technological advancement that has been beneficial for most educational purposes but also coupled with emerging challenges and potentially destabilizing effects.
Alwyn Vwen Yen Lee
semanticscholar +1 more source
Generative Artificial Intelligence (AI)’s emergence is viewed as a disruptive technological advancement that has been beneficial for most educational purposes but also coupled with emerging challenges and potentially destabilizing effects.
Alwyn Vwen Yen Lee
semanticscholar +1 more source
Business Strategy & Development
This paper responds to calls for research and conceptualizes resilience, responsiveness and reconfigurable (3Rs) capabilities required for handling disruptions in pre‐disruption, during disruption and post‐disruption stages.
M. Shamout
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This paper responds to calls for research and conceptualizes resilience, responsiveness and reconfigurable (3Rs) capabilities required for handling disruptions in pre‐disruption, during disruption and post‐disruption stages.
M. Shamout
semanticscholar +1 more source
Virtual Reality in Biomedical Education in the sense of the 3Rs
Laboratory Animals. Journal of the Laboratory Animal Science Association, 2022Article 23(2) of EU Directive 2010/63 on the protection of animals used for scientific purposes requires staff involved in the care and use of animals to be adequately educated and trained before carrying out procedures.
Martin Lemos +8 more
semanticscholar +1 more source
Total synthesis of (3R,5R) and (3R,5S)-sonnerlactones
Tetrahedron Letters, 2016In this Letter, an enantioselective synthesis of (3R,5R)-sonnerlactone and (3R,5S)-sonnerlactone have been described. Stereochemistry at C-5 position was fixed using a suitable proline catalyzed reaction during the synthesis of aliphatic segment. To accomplish this target, Mitsunobu reaction for inversion of a stereocentre and ring-closing metathesis ...
Chakrapani Sanaboina +3 more
openaire +1 more source