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3R, metodi alternativi

open access: yes
Arti Ahuwalia   +13 more
openaire   +1 more source

In Vitro Tests for Assessing the Neutralizing Ability of Snake Antivenoms: Toward the 3Rs Principles

open access: yesFrontiers in Immunology, 2021
There is an urgent need to strengthen the implementation of the 3Rs principle (Replacement, Reduction and Refinement) in the use of experimental animals in toxinological research and in the assessment of the neutralizing efficacy of snake antivenoms ...
Jose M Gutierrez   +2 more
exaly   +2 more sources
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Application of 3Rs in Caenorhabditis elegans Research for the Identification of Health-Promoting Natural Products

Planta Medica, 2023
The average age of the population is increasing worldwide, which has a profound impact on our society. This leads to an increasing demand for medicines and requires the development of new strategies to promote health during the additional years.
Martina Redl   +2 more
semanticscholar   +1 more source

The 3Rs Alone Will Not Reduce Total Animal Experimentation Numbers: A Fundamental Misunderstanding in Need of Correction

Journal of Applied Animal Ethics Research, 2023
Government authorities often view the 3Rs of “replace, reduce, refine” popularized by Russell and Burch as both a regulatory principle and a governance principle aimed at reducing the total amount of animal distress in science. They thus expect that the
Nico D. Müller
semanticscholar   +1 more source

The new paradigm in animal testing – “3Rs alternatives”

Regulatory Toxicology and Pharmacology
Regulatory studies have revolutionised over time. Today, the focus has shifted from animal toxicity testing to non-animal for regulatory safety testing.
Wen Tsin Poh, Johnson Stanslas
exaly   +2 more sources

Towards Non-Animal Testing in European Regulatory Toxicology: An Introduction to the REACH Framework and Challenges in Implementing the 3Rs

European Journal of Risk Regulation
The European Union’s REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) Regulation aims to ensure high levels of human health and environmental protection, while also promoting alternatives to animal testing.
K. Stoykova
semanticscholar   +1 more source

The 3Rs Principle in Animal Experimentation: A Legal Review of the State of the Art in Europe and the Case in Italy

open access: yesBioTech, 2021
The aim of this paper is to describe the essential points of Italian and European legislation governing the use of animals in biomedical experimentation.
Enrico Maestri
exaly   +2 more sources

Solar-Activated Titanium-Based Cu4O3/ZrO2/TiO2 Ternary Nano-Heterojunction for Rapid Photocatalytic Degradation of the Textile Dye Everzol Yellow 3RS

Catalysts
Persistent reactive azo dyes released from textile finishing are a serious threat to water systems, but effective methods using sunlight to break them down are still limited.
Saira   +8 more
semanticscholar   +1 more source

In vitro characterization of anti-inflammatory activities of 3RS, 7R, 11R-phytanic acid

Journal of Dairy Research, 2023
The aim of the research described here was to investigate the in vitro immunomodulatory effects of 3RS, 7R, 11R-phytanic acid (3RS-PHY) from the perspective of efficacy against autoimmune diseases. 3RS-PHY is a milk component with strong agonist activity
T. Nakanishi   +6 more
semanticscholar   +1 more source

3Rs Management

The increasing industrialisation and fast growth do not only pose problems related to the allocation of resources and powers, but also severely challenge the natural environment. Environmental degradation such as contaminated water, sinking groundwater levels, unhealthy soils, and polluted air has become a harsh reality in many parts of the world.
Sunanda Vincent Jaiwant   +2 more
openaire   +2 more sources

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