Results 91 to 100 of about 3,224 (210)

Matrix-free human 2D organoids recapitulate duodenal barrier and transport properties

open access: yesBMC Biology
Background Traditionally, transformed cell line monolayers have been the standard model for studying epithelial barrier and transport function. Recently, intestinal organoids were proposed as superior in recapitulating the intestine.
Kopano Valerie Masete   +4 more
doaj   +1 more source

Biomimetic robots promote the 3Rs Principle in animal testing [PDF]

open access: yesThe 2021 Conference on Artificial Life, 2021
David Bierbach   +8 more
openaire   +1 more source

A framework for the ethical use of animal‐borne devices in post‐release monitoring following rehabilitation

open access: yesWildlife Biology, EarlyView.
Rehabilitation and release contribute to conservation efforts for threatened species. Ensuring that these efforts are effective requires a good understanding of the factors which determine survival and integration of released animals into wild populations.
Jessica Harvey‐Carroll   +3 more
wiley   +1 more source

Towards High Circularity: Reconfiguring Firm‐level Strategy

open access: yesBritish Journal of Management, EarlyView.
Abstract The transition to a circular economy (CE) is increasingly recognized as a strategic priority for companies striving for more sustainable business operations. Previous CE research adopted different firm‐level strategy perspectives with varying degrees of alignment to the management literature.
Andrey Abadzhiev   +2 more
wiley   +1 more source

Insights from the Presidential Addresses to the Agricultural Economics Society

open access: yesJournal of Agricultural Economics, EarlyView.
ABSTRACT The Society's published presidential addresses have embraced a wide range of subject matter, reflecting a ‘road well travelled’ in agricultural economics. The areas covered include the development and use of data and statistics, lessons from history, sectoral analysis, land economics, international trade and international development.
David Blandford
wiley   +1 more source

Minocycline and bone marrow–derived mononuclear cells as potential therapeutics for hereditary retinal degenerations

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To assess in Royal College of Surgeons (RCS) rats if the combination of two previously documented neuroprotective strategies: minocycline administration and bone marrow–derived mononuclear cells (BM‐MNCs) intravitreal transplantation, offers enhanced neuroprotection compared with each treatment alone.
Alba Videla‐Ristol   +6 more
wiley   +1 more source

Antibody-based alternatives to animal testing for toxin detection and antitoxin evaluation

open access: yesFrontiers in Toxicology
Animal experiments have long played a central role in biomedical research and toxicology, yet their limitations in translational accuracy and ethical concerns have intensified the demand for reliable alternatives.
Seo-Hyuk Chang   +17 more
doaj   +1 more source

Cannabigerol reverses mechanical allodynia through α2A‐adrenergic modulation of thalamocortical signaling in chemotherapy‐induced neuropathy

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Background and Purpose Chemotherapy‐induced peripheral neuropathy (CIPN) is a prevalent and treatment‐resistant side effect of platinum‐based chemotherapy, characterised by mechanical allodynia. Cannabigerol (CBG), a non‐psychoactive cannabinoid, has shown antinociceptive potential, but its site and mechanism of action remain unclear.
Quinn W. Wade   +7 more
wiley   +1 more source

Peri‐Implant Inflammation Varies With Different Restorative Emergence Angles: An Histological Evaluation

open access: yesJournal of Esthetic and Restorative Dentistry, EarlyView.
ABSTRACT Objectives To histologically evaluate peri‐implant inflammatory responses associated with varying restorative emergence angles and to assess differences between buccal and lingual implant sites. Materials and Methods Six healthy male mongrel dogs received four bone‐level implants (3.8 × 7 mm) per hemi‐mandible in the posterior mandible ...
Franz J. Strauss   +7 more
wiley   +1 more source

Dynamic Capabilities as Drivers of Circular Business Models: Exploring Direct and Indirect Relationships

open access: yesJournal of Product Innovation Management, EarlyView.
ABSTRACT Academic Summary Despite the urgent need for a circular economy, firms' transition from linear to circular business models (CBMs) remains slow. While previous research suggests that dynamic capabilities are the key drivers of this transition, it assumes a direct link, overlooking that these capabilities can facilitate change but do not ...
Jörn Block   +4 more
wiley   +1 more source

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