Reporting of 3Rs Approaches in Preclinical Animal Experimental Studies—A Nationwide Study
Animals, 2023 The 3Rs aim to refine animal welfare, reduce animal numbers, and replace animal experiments. Investigations disclose that researchers are positive towards 3Rs recommendations from peers.
Merel Ritskes-Hoitinga +2 more
exaly +3 more sources
Animals, 2023 Based on the current state of science, the use of animals remains essential in bringing safe and effective medicines to patients. Respect for laboratory animal welfare and the application of 3Rs principles (the replacement, reduction, and refinement of ...
Jessica Graham +2 more
exaly +3 more sources
The Current Status of the 3Rs Principles in Animal Use in Bosnia and Herzegovina: Overview and Future Perspectives [PDF]
AnimalsThis paper presents a review of the legal and policy framework governing the use of animals in scientific procedures in Bosnia and Herzegovina, with a focus on the 3Rs (Replacement, Reduction, Refinement). National laws, subordinate regulations, official
Merima Smajlhodžić-Deljo +6 more
doaj +2 more sources
The Case for Modernizing Biomedical Research in Ireland through the Creation of an Irish 3Rs Centre
Animals, 2022 Since its publication, the 3Rs principle has provided a cornerstone for more ethical and humane biomedical and regulatory research. In Europe, the 3Rs principle has been incorporated into the European Directive 63/2010/EU, with the ultimate aim of fully ...
Dania Movia +2 more
exaly +3 more sources
Animal Research in Otorhinolaryngology: Shifts in Publication and Practice Over Two Time Periods [PDF]
Turkish Archives of OtorhinolaryngologyObjective: The aim of this bibliometric analysis is to assess the evolving trends in animal research in otorhinolaryngology over two different time periods.
Ahmet Kısa
doaj +2 more sources
A modular three in one mucosal vaccine against three antigenic clusters of ACE2 using sarbecoviruses [PDF]
npj VaccinesThe recurrent emergence of ACE2‑using sarbecovirus underscores the need for a broadly protective vaccine. Here, we mapped the antigenic landscape of sarbecovirus receptor-binding domains (RBDs) and identified three distinct clusters. We then engineered a
Lin Liu +17 more
doaj +2 more sources
25 years of applying the 3Rs principles in safety pharmacology: success stories and future perspectives [PDF]
Frontiers in PhysiologySafety pharmacology is a relatively young discipline dedicated to identifying adverse pharmacodynamic effects of new drugs that may impact human safety.
Katayoun Derakhchan +9 more
doaj +2 more sources
Implementing Culture of Care in Germany [PDF]
AnimalsThe implementation of the 3Rs principles is an essential part of daily routines and structural processes in animal research. The work of Russell and Burch regarding the 3Rs has been implemented in the field over the course of decades, but since 2002, the
Katharina Ameli, Stephanie Krämer
doaj +2 more sources
The 3Rs applied to fruits and vegetables surpluses: virtuous examples from Italy
Food Materials Research, 2023 When facing environmental issues associated with food waste, it is necessary to look upstream at the root causes. At the very beginning of the supply chain, there is the first cause of waste generation: unrecovered agriculture surpluses.
Francesca Girotto, Laura Piazza
doaj +1 more source
Open Veterinary Journal, 2023 Background: Vaccination is widely used in fish aquaculture for three primary reasons: to prevent bacterial disease spreading, minimize antibiotic use and fight antibiotic resistance.
Antonella Di-Paolo +4 more
doaj +1 more source