Results 31 to 40 of about 11,399 (169)

New Online Resource on the 3Rs Principles of Animal Research for Wildlife Biologists, Ecologists, and Conservation Managers

Conservation, 2021
The Earth’s biodiversity is in crisis. Without radical action to conserve habitats, the current rate of species extinction is predicted to accelerate even further.
Miriam A. Zemanova
doaj   +1 more source

Dataset of in vitro measured chemicals neurotoxicity

Data in Brief
To understand and describe neurotoxicity mechanistically, we must first understand the processes and responses that occur within neuronal cell systems after the administration of a chemical.
Seweryn Ulaszek, Bartek Lisowski, Sebastian Polak   +2 more
doaj   +1 more source

Hydrogel‐Based Airway‐on‐Tube With Perfusable Endothelial Lumen and Outward Epithelialization

Advanced Materials, EarlyView.
A hydrogel‐based airway‐on‐tube platform featuring a perfusable endothelial lumen and outward epithelialization is presented. The system supports primary human bronchial epithelial and lung microvascular endothelial coculture under air‐liquid interface conditions.
Ali Doryab, Jack F. Murphy, Michael Bartolf‐Kopp, Jenny C‐C Hsin, Alice Chernaik, Frank McCaughan, Yan Yan Shery Huang, Tomasz Jungst, Jürgen Groll   +8 more
wiley   +1 more source

Alliance Ruptures and Psychotherapy Outcomes: A Multilevel Meta-Analysis of Their Association. [PDF]

J Clin Psychol
ABSTRACT Objective Although two meta‐analyses have examined the relationship between rupture repair and treatment outcome, no meta‐analysis to date has investigated the association between alliance ruptures and treatment outcome. Numerous primary studies have explored this relationship; however, the methods used to assess ruptures vary considerably ...
Babl A, Gómez Penedo JM, Nimphy C, Keßel M, Crainic C, Boendermaker N, Eubanks CF.   +6 more
europepmc   +2 more sources

Programmable Pneumatic Actuator System for a Bioinspired Artificial Colon

Advanced Materials Technologies, EarlyView.
A modular soft robotic colon simulator driven by programmable pneumatic actuation is developed to mimic physiological and pathological‐like motility patterns of the large intestine. Finite element–guided design and distributed control enable anatomically realistic deformation for peristalsis, segmentation, and mass movements, supporting capsule ...
Andrew Bickerdike, Bo Tian, Xizheng Fang, Zepeng Wang, Yang Liu, Lucy Adams, Shyam Prasad   +6 more
wiley   +1 more source

Recent Advances in Transparent Microelectrode Device Architecture and Fabrication Strategies for Biomedical Applications

Advanced Materials Technologies, EarlyView.
Transparent microelectrode arrays enable simultaneous optical and electrical electrophysiology with high spatiotemporal resolution, allowing multimodal observations of dynamic biological systems. Advances in materials and device architectures improve device performance by addressing key trade‐offs between optical transparency, impedance, and ...
Michael Abraham Listyawan, Tran Bach Dang, Chi Cong Nguyen, Yee Lap Pong, Tianruo Guo, Thanh Nho Do, Hoang‐Phuong Phan   +6 more
wiley   +1 more source

Longitudinal Morphomolecular Monitoring of Head and Neck Carcinogenesis

Advanced Science, EarlyView.
A miniaturized endoscopic probe that integrates Raman spectroscopy and optical coherence tomography, enabling simultaneous molecular and structural imaging of living tissue, was developed. Applied longitudinally in a mouse model of head and neck cancer, the system tracks disease progression from precancerous lesions to invasive cancer.
Jianrong Qiu, Priyanka G. Bhosale, Vishal Kumar, Jeyrroy Gabriel, Shiyue Liu, Ciro Chiappini, Richard J. Cook, Mads S. Bergholt   +7 more
wiley   +1 more source

Improving Guest and Owner Satisfaction through a Circular Economy: An Agritourism Case Study

Tourism and Hospitality
This study examines the role of agritourism in developing strategies to promote a circular economy by applying the 3Rs (reduce, reuse, and recycle) and improving guests’ satisfaction.
Paula Tavares de Carvalho, Ricardo Jorge Raimundo, José Dias Lopes   +2 more
doaj   +1 more source

Transforming Brain Organoids Into Functional Platforms: Convergence of Engineering, Imaging, AI, and Ethics

Advanced Science, EarlyView.
Brain organoids are emerging as increasingly functional human‐relevant platforms, yet limitations in vascularization, maturation, measurement, and reproducibility still constrain their translational value. This Perspective examines how microfluidics, biofabrication, advanced imaging, electrophysiology, multimodal AI, standardization, and ethical ...
Aishwarya Pantula, Kaustubh Joshi, Swarangi Samant, Greta Babakhanova, Annie Kathuria   +4 more
wiley   +1 more source

Atlantic Horseshoe Crabs and Endotoxin Testing: Perspectives on Alternatives, Sustainable Methods, and the 3Rs (Replacement, Reduction, and Refinement)

Frontiers in Marine Science, 2020
Endotoxin testing is a vital part of quality and safety control in pharmaceutical production. The primary method for this testing in North America and Europe is the limulus amebocyte lysate (LAL) test, a critical component of which is the blood of ...
Richard Gorman
doaj   +1 more source