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The 3Rs and Humane Experimental Technique: Implementing Change
Simple Summary The 3Rs: Replacement, Reduction and Refinement, formulated by William Russell and Rex Burch, have become synonymous with the measures to improve the welfare of animals used in research and are now used as an ethical framework for improving
R. Hubrecht, Elizabeth Carter
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Background Among the eight stereoisomers of phytanic acid (PA), the 3RS, 7R, 11R-isomer is naturally occurring and is present in foods and the human body. PA is considered to have possible health benefits in the immune system.
Tomonori Nakanishi +9 more
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Dying to Go Green: The Introduction of Resomation in the United Kingdom
In an age where concern for the environment is paramount, individuals are continuously looking for ways to reduce their carbon footprint—does this now extend to in one’s own death? How can one reduce the environmental impact of their own death?
Georgina M. Robinson
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Education in laboratory animal science and the 3Rs
While laboratory animal research continues to be crucial for scientific and medical advancement, it still raises relevant ethical considerations. In order to foster public trust and support, all animal use must be relevant, responsible, competent and ...
N. Franco, A. Kerton, David I. Lewis
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3R,1R or 3R + 1R? The Teachers’ Dilemma
AbstractThe aim of education should be character building, and it begins with education of the heart. Hence, teachers in schools play a very important role in encouraging student to value diversity and regard it as an asset or resource, rather than a liability or problem. How is the situation with teachers in Malaysian school?
Liu, Ong Puay +3 more
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Opportunities for Refinement of Non-Human Primate Vaccine Studies
Non-human primates (NHPs) are used extensively in the development of vaccines and therapeutics for human disease. High standards in the design, conduct, and reporting of NHP vaccine studies are crucial for maximizing their scientific value and ...
Mark J. Prescott +3 more
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Russell and Burch's 3Rs then and now: The case of Switzerland.
Since Russell and Burch introduced and defined the 3Rs, i.e., the replacement, reduction, and refinement of animal use in research, in 1959, different definitions have emerged and been implemented in guidelines and policies.
Christian Rodriguez Perez +4 more
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Supporting the 3Rs worldwide: The 3Rs Database program
Our 3Rs databases and informative websites facilitate the implementation of 3Rs methods.
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Prácticas de economía circular inmersas en el valor compartido
La competitividad empresarial marca la posibilidad de rentabilidad en los mercados, el Valor Compartido (VC) ofrece alternativas mediante sus ejes para el desarrollo competitivo. El auge y presencia de pensamientos estratégicos hacia la sostenibilidad y
Gilberto JP Ceballos Ramírez +1 more
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Government authorities often view the 3Rs of “replace, reduce, refine” popularized by Russell and Burch as both a regulatory principle and a governance principle aimed at reducing the total amount of animal distress in science. They thus expect that the
N. Müller
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