Results 51 to 60 of about 14,239 (267)

Colorectal cancer and therapy response: a focus on the main mechanisms involved

Frontiers in Oncology, 2023
IntroductionThe latest GLOBOCAN 2021 reports that colorectal cancer (CRC) is the second leading cause of cancer-related death worldwide. Most CRC cases are sporadic and associated with several risk factors, including lifestyle habits, gut dysbiosis ...
Sara Tirendi, Sara Tirendi, Barbara Marengo, Barbara Marengo, Cinzia Domenicotti, Cinzia Domenicotti, Anna M. Bassi, Anna M. Bassi, Vanessa Almonti, Stefania Vernazza, Stefania Vernazza   +10 more
doaj   +1 more source

Implementing the 3Rs in Laboratory Animal Research—From Theory to Practice

Animals, 2023
The regulatory framework for the use of animals in research in many countries is based on the 3Rs: replacement, reduction, and refinement [...].
Garikoitz Azkona
semanticscholar   +1 more source

Inauguration of the Centro 3R for the promotion of 3Rs principles in teaching and research

ALTEX, 2018
the first European interuniversity center dedicated to promoting 3Rs principles in teaching and research was inaugurated in Pisa, Italy on March 14, 2018. The Centro 3R was spearheaded by the Universities of Pisa and Genoa. Membership is open to all Italian universities and agreements for twinning across Europe and other countries are being pursued ...
Ahluwalia, Arti, BASSI, ANNA MARIA, Milazzo, Paolo   +2 more
openaire   +4 more sources

New Online Resource on the 3Rs Principles of Animal Research for Wildlife Biologists, Ecologists, and Conservation Managers

Conservation, 2021
The Earth’s biodiversity is in crisis. Without radical action to conserve habitats, the current rate of species extinction is predicted to accelerate even further.
Miriam A. Zemanova
doaj   +1 more source

Towards Non-Animal Testing in European Regulatory Toxicology: An Introduction to the REACH Framework and Challenges in Implementing the 3Rs

European Journal of Risk Regulation
The European Union’s REACH (Registration, Evaluation, Authorisation and Restriction of Chemicals) Regulation aims to ensure high levels of human health and environmental protection, while also promoting alternatives to animal testing.
K. Stoykova
semanticscholar   +1 more source

Farmers’ perceptions and capacity for 3Rs agro-waste management in a vegetable growing area of Bangladesh

Discover Agriculture, 2023
Agriculture is responsible for giving rise to huge quantities of degradable and non-degradable waste during various farming activities. A deeper understanding of farmers’ perceptions and levels of agro-waste management capacity is essential in developing
K. Kabir, Md. Mahnur Khan Mukut, Saifur Rahman, Ataharul Chowdhury, M. Zannatun, Nahar Mukta, ·. M. A. Sarker, A. Asfour, Md. Mahnur, Khan Mukut   +9 more
semanticscholar   +1 more source

3Rs implementation in veterinary vaccine batch-release testing: Current state-of-the-art and future opportunities. A webinar and workshop report.

Biologicals (Print), 2023
Regulatory authorities require veterinary batch-release testing to confirm vaccine potency and safety, but these tests have traditionally relied on large numbers of laboratory animals.
L. Viviani, E. Balks, S. Beken, Anna-Maria Brady, Rick Clayton, F. Cliquet, Liys Desmayanti, S. Fragoeiro, Terrie Jo Hamtak, David John, Carmen Jungbaëck, M. Kalaivani, Imke Kross, Catherine Lang, Ni Made Ria Isriyanthi, L. Mallet, C. Milne, Michelle Rubbrecht, B. Siklódi, Brajesh K. Singh, G. Srinivas, P. Stickings, C. Stirling, Pushpanathan Sundram, M. Szabó, A. Thomas, M. van den Berg, A. Walker, Corinne Philippe, J. Vandeputte   +29 more
semanticscholar   +1 more source

Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals: Responses from a survey of National Control Laboratories and National Regulatory Authorities

Biologicals (Print), 2023
The UK National Centre for the Replacement, Refinement, and Reduction of Animals in Research (NC3Rs) is reviewing World Health Organization (WHO) manuals, guidelines and recommendations for vaccines and biotherapeutics to identify the extent to which ...
Elliot Lilley, M. Bruysters, P. Das, S. Gill, Richard Isbrucker, David L Jones, Anthony Holmes   +6 more
semanticscholar   +1 more source

Solar-Activated Titanium-Based Cu4O3/ZrO2/TiO2 Ternary Nano-Heterojunction for Rapid Photocatalytic Degradation of the Textile Dye Everzol Yellow 3RS

Catalysts
Persistent reactive azo dyes released from textile finishing are a serious threat to water systems, but effective methods using sunlight to break them down are still limited.
Saira, W. Abd El-Fattah, Muhammad Shahid, Sufyan Ashraf, Zeshan Ali Sandhu, A. Guesmi, N. Ben Hamadi, Mohd Farhan, Muhammad Asam Raza   +8 more
semanticscholar   +1 more source

Dataset of in vitro measured chemicals neurotoxicity

Data in Brief
To understand and describe neurotoxicity mechanistically, we must first understand the processes and responses that occur within neuronal cell systems after the administration of a chemical.
Seweryn Ulaszek, Bartek Lisowski, Sebastian Polak   +2 more
doaj   +1 more source