Results 71 to 80 of about 37,025 (306)

A General Relativistic Magnetohydrodynamics Simulation of Jet Formation

, 2004
We have performed a fully three-dimensional general relativistic magnetohydrodynamic (GRMHD) simulation of jet formation from a thin accretion disk around a Schwarzschild black hole with a free-falling corona.
Blandford R. D., Blandford R. D., Bondi H., Bondi H., G. J. Fishman, G. Richardson, Hawley J. F., K. Shibata, K.‐I. Nishikawa, Krolik J. H., Michel F. C., P. Hardee, Paczynsky B., S. Koide, T. Kudoh, Tagger M.   +15 more
core   +2 more sources

3R,1R or 3R + 1R? The Teachers’ Dilemma

Procedia - Social and Behavioral Sciences, 2010
AbstractThe aim of education should be character building, and it begins with education of the heart. Hence, teachers in schools play a very important role in encouraging student to value diversity and regard it as an asset or resource, rather than a liability or problem. How is the situation with teachers in Malaysian school?
Liu, Ong Puay, Ting, Helen, Tee, Ong Puay, Hoon, Ong Puay   +3 more
openaire   +1 more source

Wound Geometry Determines Whether Aligned‐Fiber Scaffolds Accelerate or Impede Diabetic Wound Healing: A Biased Random Walk Analysis

Advanced Healthcare Materials, EarlyView.
Wound closure is governed by geometry‐orientation coupling: aligned fibers speed migration along their axis but hinder perpendicular advance. In vivo diabetic wound experiments with composition‐matched fibrin, combined with an anisotropic diffusion (biased random‐walk) model, quantify this trade‐off and generate a healing landscape.
Yin‐Yuan Huang, Xiangjun Peng, Yuxuan Huang, Kunkoo Kim, Chengli Li, Peilun Hu, Sean J. Wang, Rohan Avula, Chun‐Yi Yang, Pengchao Ma, Shuhui Yang, Shumeng Jiang, Guy M. Genin, Xiumei Wang   +13 more
wiley   +1 more source

Improving Guest and Owner Satisfaction through a Circular Economy: An Agritourism Case Study

Tourism and Hospitality
This study examines the role of agritourism in developing strategies to promote a circular economy by applying the 3Rs (reduce, reuse, and recycle) and improving guests’ satisfaction.
Paula Tavares de Carvalho, Ricardo Jorge Raimundo, José Dias Lopes   +2 more
doaj   +1 more source

60 Years of the 3Rs symposium: Lessons learned and the road ahead.

ALTEX
When The Principles of Humane Experimental Technique was published in 1959, authors William Russell and Rex Burch had a modest goal: to make researchers think about what they were doing in the laboratory - and to do it more humanely.
Michael Balls, Rolf Bass, R. Curren, J. Fentem, Alan M. Goldberg, Thomas Hartung, Kathrin Herrmann, N. Kleinstreuer, L. Libowitz, John Parascandola, Andrew N. Rowan, Horst Spielmann, Martin L. Stephens, R. S. Thomas, K. Tsaioun   +14 more
semanticscholar   +1 more source

Integrating 3Rs approaches in WHO guidelines for the batch release testing of biologicals: Responses from a survey of vaccines and biological therapeutics manufacturers

Biologicals (Print), 2022
The UK National Centre for the Replacement, Refinement, and Reduction of Animals in Research (NC3Rs) has been tasked by the World Health Organization (WHO) to review the extent to which animal-based testing methods are described in their manuals ...
Elliot Lilley, Emmanuelle Coppens, Pradip Das, Francis Galaway, R. Isbrucker, Sarah Sheridan, P. Stickings, Anthony Holmes   +7 more
semanticscholar   +1 more source

Model‐Driven Optimization of Subcutaneous Polymer Prodrugs Achieves Cancer Remission in Mice

Advanced Healthcare Materials, EarlyView.
A pharmacokinetics/pharmacodynamics (PK/PD) model was developed to evaluate multiple dosing regimens for subcutaneously administered water‐soluble polymer prodrug for cancer therapy. The model enabled prediction of in vivo performance and contributed to the optimization of anticancer efficacy.
Anne Rodallec, Randy Lee, Jingming Cao, Sophie Marolleau, Julien Nicolas, Sébastien Benzekry   +5 more
wiley   +1 more source

Push & Pull: autonomous deployment of mobile sensors for a complete coverage

, 2009
Mobile sensor networks are important for several strategic applications devoted to monitoring critical areas. In such hostile scenarios, sensors cannot be deployed manually and are either sent from a safe location or dropped from an aircraft.
Bartolini, N., Calamoneri, T., Fusco, E. G., Massini, A., Silvestri, S.   +4 more
core   +1 more source

Oxygen Supply of Islets of Langerhans by Photosynthetically Active Microalgae in Bioprinted Co‐Cultures Maintains Their Function in a Hypoxic Environment

Advanced Healthcare Materials, EarlyView.
This study developed a bioprinted co‐culture system embedding rat pancreatic islets and Scenedesmus sp. microalgae spatially defined in close vicinity. Red light was found optimal to ensure microalgal photosynthesis while maintaining islet viability and functionality. A tailored co‐culture medium supported both cell types.
Finn Dani, Sarah Duin, Ashwini Rahul Akkineni, Susann Lehmann, Barbara Ludwig, Michael Kühl, Michael Gelinsky, Anja Lode   +7 more
wiley   +1 more source

Implementation of the 3Rs Concept in Quality Control of Biologicals: Status and Prospects (Review)

Безопасность и риск фармакотерапии
INTRODUCTION. Many countries are implementing an increasing number of alternatives to animal testing in the research, development, and quality control of medicines under the concept of 3Rs (replacement, reduction, and refinement).
L. A. Gaiderova, N. A. Alpatova, O. V. Golovinskaya, A. M. Guskov, E. K. Lipatova, M. N. Lavrova   +5 more
doaj   +1 more source